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Neuritin 1 (NRN1)

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Neuritin 1 (NRN1)
CCC H519
HGNC 17972
MGI 1915654
PubMed 19569075
RGD 621586
UniProt Q9NPD7
NRN1 is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. In vitro assays demonstrated that this protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis.
The deduced 142-amino acid protein contains a 27-amino acid secretory signal peptide at its N terminus and a 27-amino acid GPI signal peptide at its C terminus. The mature rat and human proteins are 100% identical.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH519Hu01 Recombinant Neuritin 1 (NRN1) Positive Control; Immunogen; SDS-PAGE; WB.
APH519Hu01 Active Neuritin 1 (NRN1) Cell culture; Activity Assays.
Antibodies PAH519Hu01 Polyclonal Antibody to Neuritin 1 (NRN1) WB; IHC
Assay Kits SEH519Hu ELISA Kit for Neuritin 1 (NRN1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Neuritin 1 (NRN1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Neuritin 1 (NRN1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Neuritin 1 (NRN1) Polyclonal Antibody Customized Service Offer
Assay Kits SEH519Mu ELISA Kit for Neuritin 1 (NRN1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH519Ra01 Recombinant Neuritin 1 (NRN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH519Ra01 Polyclonal Antibody to Neuritin 1 (NRN1) WB; IHC; ICC; IP.
MAH519Ra21 Monoclonal Antibody to Neuritin 1 (NRN1) WB; IHC; ICC; IP.
Assay Kits SEH519Ra ELISA Kit for Neuritin 1 (NRN1) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Neuritin: a gene induced by neural activity and neurotrophins that promotes neuritogenesis."Proc. Natl. Acad. Sci. U.S.A. 94:2648-2653(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]