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NRN1 is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. In vitro assays demonstrated that this protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis.
The deduced 142-amino acid protein contains a 27-amino acid secretory signal peptide at its N terminus and a 27-amino acid GPI signal peptide at its C terminus. The mature rat and human proteins are 100% identical.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPH519Hu01 | Recombinant Neuritin 1 (NRN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APH519Hu01 | Active Neuritin 1 (NRN1) | Cell culture; Activity Assays. | |
| Antibodies | PAH519Hu01 | Polyclonal Antibody to Neuritin 1 (NRN1) | WB; IHC |
| Assay Kits | n/a | CLIA Kit for Neuritin 1 (NRN1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Neuritin 1 (NRN1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Neuritin 1 (NRN1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Neuritin 1 (NRN1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Neuritin 1 (NRN1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | SEH519Mu | ELISA Kit for Neuritin 1 (NRN1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPH519Ra01 | Recombinant Neuritin 1 (NRN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAH519Ra01 | Polyclonal Antibody to Neuritin 1 (NRN1) | WB; IHC; ICC; IP. |
| MAH519Ra21 | Monoclonal Antibody to Neuritin 1 (NRN1) | WB; IHC; ICC; IP. | |
| Assay Kits | SEH519Ra | ELISA Kit for Neuritin 1 (NRN1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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