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Paired Box Gene 7 (PAX7)

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HUP1; PAX7B

Paired Box Gene 7 (PAX7)
CCC H447
HGNC 8621
MGI 97491
PubMed 22862948
RGD 1564360
UniProt P23759
Wiki PAX7
Paired Box Gene 7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth.
The specific function of the paired box gene 7 is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Paired Box Gene 7 (PAX7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Paired Box Gene 7 (PAX7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Paired Box Gene 7 (PAX7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Paired Box Gene 7 (PAX7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Paired Box Gene 7 (PAX7) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Paired Box Gene 7 (PAX7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Paired Box Gene 7 (PAX7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Paired Box Gene 7 (PAX7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Paired Box Gene 7 (PAX7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Paired Box Gene 7 (PAX7) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Paired Box Gene 7 (PAX7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Paired Box Gene 7 (PAX7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Paired Box Gene 7 (PAX7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Paired Box Gene 7 (PAX7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Paired Box Gene 7 (PAX7) ELISA Kit Customized Service Offer
  1. "The genomic organization and the full coding region of the human PAX7 gene."Genomics 45:168-174(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Getting the proto-Pax by the tail."J. Mol. Evol. 63:153-164(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytes."Nucleic Acids Res. 22:4574-4582(1994) [PubMed] [Europe PMC] [Abstract]
  6. "Conservation of the paired domain in metazoans and its structure in three isolated human genes."EMBO J. 8:1183-1190(1989) [PubMed] [Europe PMC] [Abstract]
  7. "Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma."Cancer Res. 54:2869-2872(1994) [PubMed] [Europe PMC] [Abstract]