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Phosphatidylinositol Glycan X (PIGX)

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Phosphatidylinositol Glycan Anchor Biosynthesis,Class X

Phosphatidylinositol Glycan X (PIGX)
CCC H409
HGNC 26046
MGI 1919334
RGD 1307289
UniProt Q8TBF5
PIGX encodes a type I transmembrane protein in the endoplasmic reticulum (ER). The protein is an essential component of glycosylphosphatidylinositol-mannosyltransferase I, which transfers the first of the four mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Studies in rat indicate that the protein is translated from a non-AUG translation initiation site. Alternative splicing results in multiple transcript variants.
The deduced 252-amino acid protein has a 22-amino acid signal peptide, a C-terminal transmembrane region, and 2 N-glycosylation sites. Human and rat Pigx proteins share 77% sequence identity. Pigx colocalized with an ER marker in transfected CHO cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphatidylinositol Glycan X (PIGX) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphatidylinositol Glycan X (PIGX) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphatidylinositol Glycan X (PIGX) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphatidylinositol Glycan X (PIGX) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphatidylinositol Glycan X (PIGX) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphatidylinositol Glycan X (PIGX) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphatidylinositol Glycan X (PIGX) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphatidylinositol Glycan X (PIGX) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphatidylinositol Glycan X (PIGX) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphatidylinositol Glycan X (PIGX) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphatidylinositol Glycan X (PIGX) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphatidylinositol Glycan X (PIGX) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphatidylinositol Glycan X (PIGX) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphatidylinositol Glycan X (PIGX) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphatidylinositol Glycan X (PIGX) ELISA Kit Customized Service Offer
  1. "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Mammalian PIG-X and yeast Pbn1p are the essential components of glycosylphosphatidylinositol-mannosyltransferase I."Mol. Biol. Cell 16:1439-1448(2005) [PubMed] [Europe PMC] [Abstract]