Phosphatidylinositol Glycan B (PIGB)

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Phosphatidylinositol Glycan Anchor Biosynthesis,Class B; GPI mannosyltransferase 3

Phosphatidylinositol Glycan B (PIGB)
PIGB encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface.
This gene is thought to encode a member of a family of dolichol-phosphate-mannose (Dol-P-Man) dependent mannosyltransferases. The PIGB cDNA encodes a predicted 554-amino acid transmembrane protein that is located in the endoplasmic reticulum. PIGB contains a small amino-terminal cytoplasmic domain and a large carboxy-terminal luminal domain.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphatidylinositol Glycan B (PIGB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphatidylinositol Glycan B (PIGB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphatidylinositol Glycan B (PIGB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphatidylinositol Glycan B (PIGB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphatidylinositol Glycan B (PIGB) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphatidylinositol Glycan B (PIGB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphatidylinositol Glycan B (PIGB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphatidylinositol Glycan B (PIGB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphatidylinositol Glycan B (PIGB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphatidylinositol Glycan B (PIGB) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphatidylinositol Glycan B (PIGB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphatidylinositol Glycan B (PIGB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphatidylinositol Glycan B (PIGB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphatidylinositol Glycan B (PIGB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphatidylinositol Glycan B (PIGB) ELISA Kit Customized Service Offer
  1. "PIG-B, a membrane protein of the endoplasmic reticulum with a large lumenal domain, is involved in transferring the third mannose of the GPI anchor."EMBO J. 15:4254-4261(1996) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Glycoinositol phospholipid anchor-defective K562 mutants with biochemical lesions distinct from those in Thy-1- murine lymphoma mutants."J. Biol. Chem. 269:6536-6542(1994) [PubMed] [Europe PMC] [Abstract]