Pregnancy Specific Beta-1-Glycoprotein 5 (PSG5)

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FL-NCA-3; PSBG-5; Fetal liver non-specific cross-reactive antigen 3

Pregnancy Specific Beta-1-Glycoprotein 5 (PSG5)
PSG5 gene contains 6 exons.The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily.
The PSG genes are tandemly oriented in a 5-prime to 3-prime direction from telomere to centromere. The CEA subgroup gene CGM11 is located at the telomeric end of the PSG gene cluster, and 6 genes belonging to a third CEA family subgroup, namely CGM13 through CGM18, are interspersed among the PSG genes.Based on this nomenclature, the CEA family is composed of the PSG subfamily, the CEACAM subfamily, and the CEACAM pseudogene (CEACAMP) subfamily.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Pregnancy Specific Beta-1-Glycoprotein 5 (PSG5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Pregnancy Specific Beta-1-Glycoprotein 5 (PSG5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Pregnancy Specific Beta-1-Glycoprotein 5 (PSG5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Pregnancy Specific Beta-1-Glycoprotein 5 (PSG5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Pregnancy Specific Beta-1-Glycoprotein 5 (PSG5) ELISA Kit Customized Service Offer
  1. "A pregnancy-specific beta 1-glycoprotein, a CEA gene family member, expressed in a human promyelocytic leukemia cell line, HL-60: structures of protein, mRNA and gene."Biochem. Biophys. Res. Commun. 163:1021-1031(1989) [PubMed] [Europe PMC] [Abstract]
  2. "Characterization of new members of the pregnancy-specific beta 1-glycoprotein family."Mol. Cell. Biochem. 106:161-170(1991) [PubMed] [Europe PMC] [Abstract]
  3. "Carcinoembryonic antigen gene family: molecular cloning of cDNA for a PS-beta-G/FL-NCA glycoprotein with a novel domain arrangement."Biochem. Biophys. Res. Commun. 161:525-535(1989) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]