Pregnancy Specific Beta-1-Glycoprotein 4 (PSG4)

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CGM4; PSG9; PSBG-4; Pregnancy-specific glycoprotein 9

Pregnancy Specific Beta-1-Glycoprotein 4 (PSG4)
The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. PSG9, which had been thought to be a novel gene, is in fact an allelic variant of PSG4 that differs by 6 bp in the coding region. (The allelic variant that had been referred to as PSG9 should not be confused with the PSG9 gene.)

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Pregnancy Specific Beta-1-Glycoprotein 4 (PSG4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Pregnancy Specific Beta-1-Glycoprotein 4 (PSG4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Pregnancy Specific Beta-1-Glycoprotein 4 (PSG4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Pregnancy Specific Beta-1-Glycoprotein 4 (PSG4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Pregnancy Specific Beta-1-Glycoprotein 4 (PSG4) ELISA Kit Customized Service Offer
  1. "The human pregnancy-specific glycoprotein genes are tightly linked on the long arm of chromosome 19 and are coordinately expressed."Biochem. Biophys. Res. Commun. 167:848-859(1990) [PubMed] [Europe PMC] [Abstract]
  2. ErratumBiochem. Biophys. Res. Commun. 168:1325-1325(1990) [PubMed] [Europe PMC] [Abstract]
  3. "Characterization of two new members of the pregnancy-specific beta 1-glycoprotein family from the myeloid cell line KG-1 and suggestion of two distinct classes of transcription unit."Biochemistry 29:10213-10218(1990) [PubMed] [Europe PMC] [Abstract]
  4. "Characterization of new members of the pregnancy-specific beta 1-glycoprotein family."Mol. Cell. Biochem. 106:161-170(1991) [PubMed] [Europe PMC] [Abstract]
  5. "Characterization of cDNA encoding novel pregnancy-specific glycoprotein variants."Biochem. Biophys. Res. Commun. 211:656-664(1995) [PubMed] [Europe PMC] [Abstract]
  6. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  7. "cDNA cloning demonstrates the expression of pregnancy-specific glycoprotein genes, a subgroup of the carcinoembryonic antigen gene family, in fetal liver."Biochem. Biophys. Res. Commun. 163:1197-1209(1989) [PubMed] [Europe PMC] [Abstract]
  8. "Characterization of cDNA encoding human pregnancy-specific beta 1-glycoprotein from placenta and extraplacental tissues and their comparison with carcinoembryonic antigen."DNA 7:545-555(1988) [PubMed] [Europe PMC] [Abstract]