Retinol Dehydrogenase 10 (RDH10)
[Edit]SDR16C4; Short Chain Dehydrogenase/Reductase Family 16C,Member 4
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RDH10 generates all-trans retinal from all-trans retinol and may plan an important role in the photic visual cycle. All-trans retinal is isomerized to 11-cis retinal by the retinal G protein-coupled receptor (RGR) when the retinal pigment epithelium (RPE) is illuminated.
The deduced 341-amino acid RDH10 protein has a calculated molecular mass of about 38 kD. It shares significant sequence homology with other SDRs, and it shares 100% and 98.6% amino acid identity with the bovine and murine Rdh10 proteins, respectively. Northern blot analysis of bovine tissues detected a 3-kb transcript only in RPE. Real-time PCR revealed high expression in RPE and low expression in most other tissues tested.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Retinol Dehydrogenase 10 (RDH10) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Retinol Dehydrogenase 10 (RDH10) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Retinol Dehydrogenase 10 (RDH10) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Retinol Dehydrogenase 10 (RDH10) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Retinol Dehydrogenase 10 (RDH10) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Retinol Dehydrogenase 10 (RDH10) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Retinol Dehydrogenase 10 (RDH10) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Retinol Dehydrogenase 10 (RDH10) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Retinol Dehydrogenase 10 (RDH10) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Retinol Dehydrogenase 10 (RDH10) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Retinol Dehydrogenase 10 (RDH10) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Retinol Dehydrogenase 10 (RDH10) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Retinol Dehydrogenase 10 (RDH10) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Retinol Dehydrogenase 10 (RDH10) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Retinol Dehydrogenase 10 (RDH10) | ELISA Kit Customized Service Offer |
- "Cloning and characterization of a novel all-trans retinol short-chain dehydrogenase/reductase from the RPE."Invest. Ophthalmol. Vis. Sci. 43:3365-3372(2002) [PubMed] [Europe PMC] [Abstract]
- "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Genomic organization and transcription of the human retinol dehydrogenase 10 (RDH10) gene."FEBS Lett. 554:59-66(2003) [PubMed] [Europe PMC] [Abstract]