≡

RNA Polymerase II Associated Protein 1 (RPAP1)

[Edit]

RNA Polymerase II Associated Protein 1 (RPAP1)
CCC H212
HGNC 24567
MGI 1916175
PubMed 15282305
RGD 1590891
UniProt Q9BWH6
By sequencing clones obtained from a size-fractionated fetal brain cDNA library, Nagase et al. (2000) cloned RPAP1, which they designated KIAA1403. The transcript contains repetitive elements in its 3-prime UTR, and the deduced protein contains 1,337 amino acids. RT-PCR ELISA detected moderate expression in all adult and fetal tissues and specific adult brain regions examined.
Jeronimo et al. (2007) identified RPAP1 as an RNA polymerase II-associated protein in HEK293 human embryonic kidney cells and obtained a full-length RPAP1 cDNA by database and sequence analyses. The deduced 1,393-amino acid protein contains an ARM domain that mediates protein-protein interactions.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Polymerase II Associated Protein 1 (RPAP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Polymerase II Associated Protein 1 (RPAP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Polymerase II Associated Protein 1 (RPAP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Polymerase II Associated Protein 1 (RPAP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Polymerase II Associated Protein 1 (RPAP1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Polymerase II Associated Protein 1 (RPAP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Polymerase II Associated Protein 1 (RPAP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Polymerase II Associated Protein 1 (RPAP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Polymerase II Associated Protein 1 (RPAP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Polymerase II Associated Protein 1 (RPAP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Polymerase II Associated Protein 1 (RPAP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Polymerase II Associated Protein 1 (RPAP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Polymerase II Associated Protein 1 (RPAP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Polymerase II Associated Protein 1 (RPAP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Polymerase II Associated Protein 1 (RPAP1) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:65-73(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Analysis of the DNA sequence and duplication history of human chromosome 15." Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  7. "RPAP1, a novel human RNA polymerase II-associated protein affinity purified with recombinant wild-type and mutated polymerase subunits."Mol. Cell. Biol. 24:7043-7058(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme."Mol. Cell 27:262-274(2007) [PubMed] [Europe PMC] [Abstract]
  9. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  10. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  14. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]