Serine Incorporator 3 (SERINC3)

[Edit]

AIGP1; DIFF33; SBBI99; TDE; TDE1; TMS-1; Tumor differentially expressed protein 1

Serine Incorporator 3 (SERINC3)
TDE1 overexpression in transfected rat cells resulted in reduced contact inhibition with formation of robust foci. In transfected rat and human cell lines, TDE1 overexpression reduced apoptosis caused by serum starvation or etoposide treatment, as shown by reduced caspase-3 activation and DNA laddering. TDE1 did not alter cell growth rate, immortalization, or motility. The 473-amino acid protein has a predicted molecular mass of 52 kD. Use of an alternative polyadenylation site results in a splice variant lacking 61 amino acids. Like the mouse protein, with which it shares 78% sequence homology, human TDE1 contains several predicted hydrophobic alpha helices characteristic of transmembrane proteins, and it has several potential phosphorylation sites.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Serine Incorporator 3 (SERINC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Serine Incorporator 3 (SERINC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Serine Incorporator 3 (SERINC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Serine Incorporator 3 (SERINC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Serine Incorporator 3 (SERINC3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Serine Incorporator 3 (SERINC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Serine Incorporator 3 (SERINC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Serine Incorporator 3 (SERINC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Serine Incorporator 3 (SERINC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Serine Incorporator 3 (SERINC3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Serine Incorporator 3 (SERINC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Serine Incorporator 3 (SERINC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Serine Incorporator 3 (SERINC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Serine Incorporator 3 (SERINC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Serine Incorporator 3 (SERINC3) ELISA Kit Customized Service Offer
  1. "The human TDE gene homologue: localization to 20q13.1-13.3 and variable expression in human tumor cell lines and tissue."Mol. Carcinog. 26:189-200(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]