Suppressors Of Cytokine Signaling 5 (SOCS5)

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CIS6; CISH6; Cish5; SOCS-5; Cytokine-inducible SH2 protein 6; Cytokine-inducible SH2-containing protein 5

Suppressors Of Cytokine Signaling 5 (SOCS5)
SOCS5 contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.The human protein is 95% similar to the mouse protein. It contains an N-terminal region of 378 amino acids, followed by the SH2 domain, which is immediately adjacent to the C-terminal SOCS box. Northern blot analysis revealed wide expression of a 4.2-kb transcript in tissues and in all myeloma cell lines tested.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Suppressors Of Cytokine Signaling 5 (SOCS5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Suppressors Of Cytokine Signaling 5 (SOCS5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Suppressors Of Cytokine Signaling 5 (SOCS5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Suppressors Of Cytokine Signaling 5 (SOCS5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Suppressors Of Cytokine Signaling 5 (SOCS5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Suppressors Of Cytokine Signaling 5 (SOCS5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Suppressors Of Cytokine Signaling 5 (SOCS5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Suppressors Of Cytokine Signaling 5 (SOCS5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Suppressors Of Cytokine Signaling 5 (SOCS5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Suppressors Of Cytokine Signaling 5 (SOCS5) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Suppressors Of Cytokine Signaling 5 (SOCS5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Suppressors Of Cytokine Signaling 5 (SOCS5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Suppressors Of Cytokine Signaling 5 (SOCS5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Suppressors Of Cytokine Signaling 5 (SOCS5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Suppressors Of Cytokine Signaling 5 (SOCS5) ELISA Kit Customized Service Offer
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  3. "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signaling."J. Biol. Chem. 280:7038-7048(2005) [PubMed] [Europe PMC] [Abstract]