Six Transmembrane Epithelial Antigen Of The Prostate 1 (STEAP1)
[Edit]PRSS24; STEAP; Metalloreductase STEAP1
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STEAP1 is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions.One novel gene that was highly expressed in advanced prostate cancer encoded a 339-amino acid protein with 6 potential membrane-spanning regions flanked by hydrophilic N- and C-terminal domains. This structure suggested a potential function as a channel or transporter protein. This gene, named STEAP for 'six-transmembrane epithelial antigen of the prostate,' was expressed predominantly in human prostate tissue and was upregulated in multiple cancer cell lines, including prostate, bladder, colon, ovarian, and Ewing sarcoma.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Six Transmembrane Epithelial Antigen Of The Prostate 1 (STEAP1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Six Transmembrane Epithelial Antigen Of The Prostate 1 (STEAP1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Six Transmembrane Epithelial Antigen Of The Prostate 1 (STEAP1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Six Transmembrane Epithelial Antigen Of The Prostate 1 (STEAP1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Six Transmembrane Epithelial Antigen Of The Prostate 1 (STEAP1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Six Transmembrane Epithelial Antigen Of The Prostate 1 (STEAP1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Six Transmembrane Epithelial Antigen Of The Prostate 1 (STEAP1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Six Transmembrane Epithelial Antigen Of The Prostate 1 (STEAP1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Six Transmembrane Epithelial Antigen Of The Prostate 1 (STEAP1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Six Transmembrane Epithelial Antigen Of The Prostate 1 (STEAP1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Six Transmembrane Epithelial Antigen Of The Prostate 1 (STEAP1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Six Transmembrane Epithelial Antigen Of The Prostate 1 (STEAP1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Six Transmembrane Epithelial Antigen Of The Prostate 1 (STEAP1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Six Transmembrane Epithelial Antigen Of The Prostate 1 (STEAP1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Six Transmembrane Epithelial Antigen Of The Prostate 1 (STEAP1) | ELISA Kit Customized Service Offer |
- "STEAP: a prostate-specific cell-surface antigen highly expressed in human prostate tumors."Proc. Natl. Acad. Sci. U.S.A. 96:14523-14528(1999) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
- "Human chromosome 7: DNA sequence and biology." Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "The Steap proteins are metalloreductases."Blood 108:1388-1394(2006) [PubMed] [Europe PMC] [Abstract]