Sulfatase 2 (SULF2)

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HSULF-2; Extracellular sulfatase Sulf-2

Sulfatase 2 (SULF2)
Sulfatase 2contains an N-terminal signal sequence, followed by a sulfatase domain, a hydrophilic region, and a C-terminal substrate recognition domain.SULF2 shares about 64% identity with SULF1 and 94% identity with mouse Sulf2. PCR detected SULF2 expression in most human tissues examined, with highest levels in ovary, skeletal muscle, stomach, brain, uterus, heart, kidney, and placenta. Western blot analysis of transfected Chinese hamster ovary (CHO) cells and culture medium detected SULF2 proteins with apparent molecular masses of 132, 64, and 60 kD in the culture medium. Treatment with furin inhibitors resulted in a single 132-kD species, and treatment with N-glycanase reduced the molecular mass from 132 kD to 100 kD.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH107Hu01 Recombinant Sulfatase 2 (SULF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH107Hu01 Polyclonal Antibody to Sulfatase 2 (SULF2) WB; ICC/IF
LAH107Hu81 FITC-Linked Polyclonal Antibody to Sulfatase 2 (SULF2) WB; IHC; ICC; IF.
LAH107Hu71 Biotin-Linked Polyclonal Antibody to Sulfatase 2 (SULF2) WB; IHC; ICC.
MAH107Hu21 Monoclonal Antibody to Sulfatase 2 (SULF2) WB; IHC; ICC; IP.
Assay Kits SEH107Hu ELISA Kit for Sulfatase 2 (SULF2) Enzyme-linked immunosorbent assay for Antigen Detection.
SCH107Hu CLIA Kit for Sulfatase 2 (SULF2) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH107Mu01 Recombinant Sulfatase 2 (SULF2) Positive Control; Immunogen; SDS-PAGE; WB.
RPH107Mu02 Recombinant Sulfatase 2 (SULF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH107Mu01 Polyclonal Antibody to Sulfatase 2 (SULF2) WB,IHC
PAH107Mu02 Polyclonal Antibody to Sulfatase 2 (SULF2) WB; IHC; ICC; IP.
Assay Kits SEH107Mu ELISA Kit for Sulfatase 2 (SULF2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sulfatase 2 (SULF2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sulfatase 2 (SULF2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sulfatase 2 (SULF2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sulfatase 2 (SULF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sulfatase 2 (SULF2) ELISA Kit Customized Service Offer
  1. "Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans."J. Biol. Chem. 277:49175-49185(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 6:337-345(1999) [PubMed] [Europe PMC] [Abstract]
  3. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
  4. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
  9. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]