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Sulfotransferase Family 2A, Member 1 (SULT2A1)

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STD; HST; DHEA-ST; Sulfotransferase Family,Cytosolic,2A,Dehydroepiandrosterone(DHEA)-Preferring 1; Bile salt sulfotransferase; Dehydroepiandrosterone sulfotransferase

Sulfotransferase Family 2A, Member 1 (SULT2A1)
CCC H099
HGNC 11458
MGI 98430
PubMed 17687072
RGD 621337
UniProt Q06520
Wiki SULT2A1
SULT2A1 encodes a member of the sulfotransferase family. Sulfotransferases aid in the metabolism of drugs and endogenous compounds by converting these substances into more hydrophilic water-soluble sulfate conjugates that can be easily excreted. This protein catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands, and may have a role in the inherited adrenal androgen excess in women with polycystic ovary syndrome. This gene has an important role in the sulfation of both bile acids and steroids in the liver and adrenals. The human adrenal form of this enzyme is physically, immunologically, and kinetically similar, perhaps identical, to the liver form. Dehydroepiandrosterone sulfate is quantitatively one of the major steroids secreted from the adrenal cortex.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sulfotransferase Family 2A, Member 1 (SULT2A1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sulfotransferase Family 2A, Member 1 (SULT2A1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sulfotransferase Family 2A, Member 1 (SULT2A1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sulfotransferase Family 2A, Member 1 (SULT2A1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sulfotransferase Family 2A, Member 1 (SULT2A1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sulfotransferase Family 2A, Member 1 (SULT2A1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sulfotransferase Family 2A, Member 1 (SULT2A1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sulfotransferase Family 2A, Member 1 (SULT2A1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sulfotransferase Family 2A, Member 1 (SULT2A1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sulfotransferase Family 2A, Member 1 (SULT2A1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sulfotransferase Family 2A, Member 1 (SULT2A1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sulfotransferase Family 2A, Member 1 (SULT2A1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sulfotransferase Family 2A, Member 1 (SULT2A1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sulfotransferase Family 2A, Member 1 (SULT2A1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sulfotransferase Family 2A, Member 1 (SULT2A1) ELISA Kit Customized Service Offer
  1. "Cloning and expression of human liver dehydroepiandrosterone sulphotransferase."Biochem. J. 289:233-240(1993) [PubMed] [Europe PMC] [Abstract]
  2. "Human liver dehydroepiandrosterone sulfotransferase: molecular cloning and expression of cDNA."Mol. Pharmacol. 41:865-872(1992) [PubMed] [Europe PMC] [Abstract]
  3. "Human fetal adrenal hydroxysteroid sulphotransferase: cDNA cloning, stable expression in V79 cells and functional characterisation of the expressed enzyme."Mol. Cell. Endocrinol. 112:53-60(1995) [PubMed] [Europe PMC] [Abstract]
  4. "Structural characterization and expression of the human dehydroepiandrosterone sulfotransferase gene."DNA Cell Biol. 14:511-518(1995) [PubMed] [Europe PMC] [Abstract]
  5. "Human dehydroepiandrosterone sulfotransferase gene: molecular cloning and structural characterization."DNA Cell Biol. 14:331-341(1995) [PubMed] [Europe PMC] [Abstract]
  6. "Molecular cloning of the alcohol/hydroxysteroid form (hSTa) of sulfotransferase from human liver."Biochem. Biophys. Res. Commun. 187:448-454(1992) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Human liver steroid sulphotransferase sulphates bile acids."Biochem. J. 272:597-604(1990) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  11. "Crystal structure of SULT2A3, human hydroxysteroid sulfotransferase."FEBS Lett. 475:61-64(2000) [PubMed] [Europe PMC] [Abstract]
  12. "Crystal structure of human dehydroepiandrosterone sulphotransferase in complex with substrate."Biochem. J. 364:165-171(2002) [PubMed] [Europe PMC] [Abstract]
  13. "Identifying androsterone (ADT) as a cognate substrate for human dehydroepiandrosterone sulfotransferase (DHEA-ST) important for steroid homeostasis: structure of the enzyme-ADT complex."J. Biol. Chem. 279:2689-2696(2004) [PubMed] [Europe PMC] [Abstract]