Synaptotagmin XVI (SYT16)
[Edit]Yt14r; CHR14SYT; Strep14; Synaptotagmin 14-like protein; Synaptotagmin XIV-related protein
![Synaptotagmin XVI (SYT16)](/upload/item/img/Synaptotagmin-XVI-(SYT16)-97079.jpg)
By searching databases for sequences encoding synaptotagmin-like C2 domains, Fukuda (2003) identified mouse and human SYT14 and SYT16, which they called STREP14. The deduced mouse and human STREP14 proteins contain 639 and 625 amino acids, respectively. Both have C-terminal C-type tandem C2 domains, but they lack the N-terminal transmembrane domain found in other synaptotagmins. RT-PCR detected highest Strep14 expression in mouse heart and testis, with weaker expression in kidney and lung. In mouse embryos, expression was weak on day 7 and strong on days 11, 15, and 17. mouse Strep14 showed relatively weak homooligomerization and heterooligomerization with Syt14, irrespective of the presence of Ca(2+). The C2 domains of Strep14 bound liposomes made up of phosphatidylcholine and phosphatidylserine.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Synaptotagmin XVI (SYT16) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Synaptotagmin XVI (SYT16) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Synaptotagmin XVI (SYT16) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Synaptotagmin XVI (SYT16) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Synaptotagmin XVI (SYT16) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Synaptotagmin XVI (SYT16) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Synaptotagmin XVI (SYT16) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Synaptotagmin XVI (SYT16) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Synaptotagmin XVI (SYT16) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Synaptotagmin XVI (SYT16) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Synaptotagmin XVI (SYT16) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Synaptotagmin XVI (SYT16) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Synaptotagmin XVI (SYT16) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Synaptotagmin XVI (SYT16) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Synaptotagmin XVI (SYT16) | ELISA Kit Customized Service Offer |
- "Molecular cloning, expression, and characterization of a novel class of synaptotagmin (Syt XIV) conserved from Drosophila to humans."J. Biochem. 133:641-649(2003) [PubMed] [Europe PMC] [Abstract]
- "Synaptotagmin gene content of the sequenced genomes."BMC Genomics 5:43-43(2004) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Genomic analysis of synaptotagmin genes."Genomics 77:43-49(2001) [PubMed] [Europe PMC] [Abstract]