![Synaptotagmin VII (SYT7)](/upload/item/img/Synaptotagmin-VII-(SYT7)-97077.jpg)
Synaptotagmins, such as SYT7, are brain-specific calcium-dependent phospholipid-binding proteins that play a role in synaptic exocytosis and neurotransmitter release. The predicted 403-amino acid human and rat proteins are 98% identical. Northern blot analysis revealed that synaptotagmin VII is expressed as 4.4- and 7.5-kb mRNAs in a variety of human adult and fetal tissues, including those from different regions of the brain.The 2 minor isoforms contain unique insertions in the spacer domain between the transmembrane and C2 domains. Similar results were obtained with respect to human SYT7. Expression of fluorescence-tagged Syt7 in rat pheochromocytoma cells revealed localization in the perinuclear region, where it colocalized with a Golgi marker protein, and localization in the tips of neurites.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Synaptotagmin VII (SYT7) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Synaptotagmin VII (SYT7) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Synaptotagmin VII (SYT7) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | SEH077Hu | ELISA Kit for Synaptotagmin VII (SYT7) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Synaptotagmin VII (SYT7) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Synaptotagmin VII (SYT7) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Synaptotagmin VII (SYT7) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Synaptotagmin VII (SYT7) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Synaptotagmin VII (SYT7) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Synaptotagmin VII (SYT7) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Synaptotagmin VII (SYT7) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Synaptotagmin VII (SYT7) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Synaptotagmin VII (SYT7) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Synaptotagmin VII (SYT7) | ELISA Kit Customized Service Offer |
- "Transcript mapping of the human chromosome 11q12-q13.1 gene-rich region identifies several newly described conserved genes."Genomics 49:419-429(1998) [PubMed] [Europe PMC] [Abstract]
- "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Solution structure of the first C2 domain of synaptotagmin VII."Submitted (JUN-2006) to the PDB data bank