The synaptotagmins are a family of type III membrane proteins characterized by cytoplasmic repeats related to the protein kinase C regulatory (C2) domains which are thought to bind calcium. The synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules.
Hudson and Birnbaum (1995) cloned a synaptotagmin cDNA from a rat adipose tissue cDNA library. The sequence predicts a 386-amino acid protein with 49% identity to synaptotagmins 1 and 2 . The 1.7-kb synaptotagmin-5 mRNA is expressed in rat kidney, adipose tissue, lung and heart, and at higher levels in brain. An antibody to the SYT5 gene product detected an approximately 50-kD protein.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Synaptotagmin V (SYT5) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Synaptotagmin V (SYT5) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Synaptotagmin V (SYT5) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Synaptotagmin V (SYT5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Synaptotagmin V (SYT5) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Synaptotagmin V (SYT5) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Synaptotagmin V (SYT5) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Synaptotagmin V (SYT5) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Synaptotagmin V (SYT5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Synaptotagmin V (SYT5) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Synaptotagmin V (SYT5) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Synaptotagmin V (SYT5) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Synaptotagmin V (SYT5) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Synaptotagmin V (SYT5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Synaptotagmin V (SYT5) | ELISA Kit Customized Service Offer |
- "Human synaptotagmin V (SYT5): sequence, genomic structure, and chromosomal location."Genomics 42:165-169(1997) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]