Transcription Factor AP2 Gamma (TFAP2g)

[Edit]

TFAP2C; AP2-GAMMA; ERF1; TFAP2G; hAP-2g; Activating Enhancer-Binding Protein 2 Gamma; Estrogen Receptor Factor 1

Transcription Factor AP2 Gamma (TFAP2g)
TFAP2g is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. The deduced 450-amino acid protein has a calculated molecular mass of about 48 kD. TFAP2C and TFAP2A share 65% sequence identity overall and 76% identity in their C-terminal halves, which contain the DNA-binding and dimerization domains.TFAP2C gene contains 7 exons and spans about 8.4 kb. Exon 1 is untranslated. The promoter region of TFAP2C contains no canonical TATA and CCAAT boxes, but it does have a cluster of CpG islands, as well as binding sites for OCT1 and AP2.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transcription Factor AP2 Gamma (TFAP2g) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transcription Factor AP2 Gamma (TFAP2g) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transcription Factor AP2 Gamma (TFAP2g) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transcription Factor AP2 Gamma (TFAP2g) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transcription Factor AP2 Gamma (TFAP2g) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transcription Factor AP2 Gamma (TFAP2g) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transcription Factor AP2 Gamma (TFAP2g) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transcription Factor AP2 Gamma (TFAP2g) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transcription Factor AP2 Gamma (TFAP2g) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transcription Factor AP2 Gamma (TFAP2g) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transcription Factor AP2 Gamma (TFAP2g) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transcription Factor AP2 Gamma (TFAP2g) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transcription Factor AP2 Gamma (TFAP2g) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transcription Factor AP2 Gamma (TFAP2g) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transcription Factor AP2 Gamma (TFAP2g) ELISA Kit Customized Service Offer
  1. "Chromosomal mapping of the human and mouse homologues of two new members of the AP-2 family of transcription factors."Genomics 35:262-264(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Identification of ERF-1 as a member of the AP2 transcription factor family."Proc. Natl. Acad. Sci. U.S.A. 94:4342-4347(1997) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator."Nat. Genet. 29:469-474(2001) [PubMed] [Europe PMC] [Abstract]
  7. "Human CREB-binding protein/p300-interacting transactivator with ED-rich tail (CITED) 4, a new member of the CITED family, functions as a co-activator for transcription factor AP-2."J. Biol. Chem. 277:8559-8565(2002) [PubMed] [Europe PMC] [Abstract]
  8. "Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo."J. Biol. Chem. 277:30798-30804(2002) [PubMed] [Europe PMC] [Abstract]
  9. "Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2."J. Biol. Chem. 278:16021-16029(2003) [PubMed] [Europe PMC] [Abstract]
  10. "Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2gamma transcription factor."Cancer Res. 64:8256-8261(2004) [PubMed] [Europe PMC] [Abstract]
  11. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  12. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  13. "The interaction of KCTD1 with transcription factor AP-2alpha inhibits its transactivation."J. Cell. Biochem. 106:285-295(2009) [PubMed] [Europe PMC] [Abstract]
  14. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  15. "Differential regulation of estrogen receptor alpha expression in breast cancer cells by metastasis-associated protein 1."Cancer Res. 74:1484-1494(2014) [PubMed] [Europe PMC] [Abstract]