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Talin 2 (TLN2)

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Talin 2 (TLN2)
CCC H015
HGNC 15447
MGI 1917799
PubMed 11527381
RGD 1565416
UniProt Q9Y4G6
Wiki TLN2
TLN2 encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton.
The deduced 2,532-amino acid protein contains a FERM domain. In TLN1, the FERM domain binds the cytodomains of beta-1 and beta-3 integrins, as well as to F-actin and other proteins. TLN2 shares 74% identity with TLN1, and the N- and C-terminal regions of TLN2 are highly conserved across species.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH015Hu01 Recombinant Talin 2 (TLN2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH015Hu01 Polyclonal Antibody to Talin 2 (TLN2) WB; IHC; ICC; IP.
MAH015Hu21 Monoclonal Antibody to Talin 2 (TLN2) WB; IHC; ICC; IP.
Assay Kits SEH015Hu ELISA Kit for Talin 2 (TLN2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Talin 2 (TLN2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Talin 2 (TLN2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Talin 2 (TLN2) Polyclonal Antibody Customized Service Offer
Assay Kits SEH015Mu ELISA Kit for Talin 2 (TLN2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Talin 2 (TLN2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Talin 2 (TLN2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Talin 2 (TLN2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Talin 2 (TLN2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Talin 2 (TLN2) ELISA Kit Customized Service Offer
  1. "Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin."Nature 420:85-89(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Analysis of the mammalian talin2 gene TLN2."Biochem. Biophys. Res. Commun. 286:880-885(2001) [PubMed] [Europe PMC] [Abstract]
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