Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2)
[Edit]QCR2; UQCR2; Cytochrome b-c1 complex subunit 2, mitochondrial; Complex III subunit 2; Core protein II
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The amount of PPARG, PPARG coactivator-1-alpha (PPARGC1A), ubiquinol-cytochrome c oxidoreductase core 2 subunit (UQCRC2), cytochrome c oxidase subunit I (MTCO1), uncoupling protein-2 (UCP2), and ATP synthase H(+)-transporting mitochondrial F1 complex (F1-ATP synthase) were markedly reduced in the low capacity runner rats in comparison with the high capacity runners.
The uniform decline in these proteins was consistent with the hypothesis that reduced aerobic metabolism plays a causal role in the development of the differences between the low capacity runner and high capacity runner rats. impairment of mitochondrial function may link reduced fitness to cardiovascular and metabolic disease.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPG916Mu01 | Recombinant Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPG916Mu02 | Recombinant Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAG916Mu01 | Polyclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | WB; IHC; ICC; IP. |
| PAG916Mu02 | Polyclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | WB; IHC; ICC; IP. | |
| Assay Kits | SEG916Mu | ELISA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) | ELISA Kit Customized Service Offer |
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- , Submitted (MAR-2007) to UniProtKB
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- "Mitochondrial complex III deficiency caused by a homozygous UQCRC2 mutation presenting with neonatal-onset recurrent metabolic decompensation."Hum. Mutat. 34:446-452(2013) [PubMed] [Europe PMC] [Abstract]