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Myozenin 1 (MYOZ1)

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FATZ; CS2; Calsarcin 2; Filamin-actinin-and telethonin-binding protein

Myozenin 1 (MYOZ1)
CCC G839
HGNC 13752
MGI 1929471
PubMed 17254821
RGD 1561064
UniProt Q9NP98
Wiki MYOZ1
Calcineurin is a calcium/calmodulin-dependent serine-threonine phosphatase that plays an important role in transducing calcium-dependent signals in a variety of cell types. Calcineurin has also been shown to have a profound influence on the properties of striated muscle cells, including cardiac muscle.
Calsarcin-2 encodes a 299-amino acid protein, which shows the highest sequence homology with calsarcin-1 in the N and C termini.Calsarcins 1 and 2 are expressed in developing cardiac and skeletal muscle during embryogenesis, but calsarcin-1 is expressed specifically in adult cardiac and slow-twitch skeletal muscle as 1.6- and 2.6-kb transcripts, whereas calsarcin-2 is expressed only in adult fast skeletal muscle as a 1.6-kb transcript.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myozenin 1 (MYOZ1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myozenin 1 (MYOZ1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myozenin 1 (MYOZ1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myozenin 1 (MYOZ1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myozenin 1 (MYOZ1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myozenin 1 (MYOZ1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myozenin 1 (MYOZ1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myozenin 1 (MYOZ1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myozenin 1 (MYOZ1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myozenin 1 (MYOZ1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myozenin 1 (MYOZ1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myozenin 1 (MYOZ1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myozenin 1 (MYOZ1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myozenin 1 (MYOZ1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myozenin 1 (MYOZ1) ELISA Kit Customized Service Offer
  1. "FATZ, a filamin-, actinin-, and telethonin-binding protein of the Z-disc of skeletal muscle."J. Biol. Chem. 275:41234-41242(2000) [PubMed] [Europe PMC] [Abstract].
  2. "Calsarcins, a novel family of sarcomeric calcineurin-binding proteins."Proc. Natl. Acad. Sci. U.S.A. 97:14632-14637(2000) [PubMed] [Europe PMC] [Abstract].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract].
  4. "Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins."J. Biol. Chem. 277:13998-14004(2002) [PubMed] [Europe PMC] [Abstract]
  5. "The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins."J. Cell Sci. 118:3739-3749(2005) [PubMed] [Europe PMC] [Abstract]