Breast Cancer Anti-Estrogen Resistance 3 (BCAR3)

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NSP2; SH2D3B; Novel SH2-containing protein 2; SH2 domain-containing protein 3B

Breast Cancer Anti-Estrogen Resistance 3 (BCAR3)
BCAR3 encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48.The deduced 825-amino acid BCAR3 protein contains a putative Src homology 2 (SH2) domain and sequences homologous to yeast CDC48. Northern blot analysis detected abundant expression of a 3.4-kb BCAR3 transcript in heart, placenta, skeletal muscle, spleen, prostate, testis, ovary, small intestine, colon, fetal kidney, and several cancer cell lines, but not in nonmalignant breast tissue; a 6-kb BCAR3 transcript was also detected in skeletal muscle and heart.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG768Hu01 Recombinant Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG768Hu01 Polyclonal Antibody to Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) WB; IHC; ICC; IP.
MAG768Hu21 Monoclonal Antibody to Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) WB; IHC; ICC; IP.
Assay Kits SEG768Hu ELISA Kit for Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) ELISA Kit Customized Service Offer
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