GA Binding Protein Transcription Factor Beta (GABPb)
[Edit]GABPB2; BABPB2; E4TF1; E4TF1-47; E4TF1-53; E4TF1B; GABPB1; NRF2B1; NRF2B2; Nuclear respiratory factor 2; Transcription factor E4TF1-47
![GA Binding Protein Transcription Factor Beta (GABPb)](/upload/item/img/GA-Binding-Protein-Transcription-Factor-Beta-(GABPb)-96692.jpg)
GABPb encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene. The predicted GABPB1 and GABPB2 subunits contain 383 and 347 amino acids, respectively, and are highly homologous. The N-terminal 332 amino acids of GABPB1 and GABPB2, including 4 tandemly repeated Notch motifs, are identical; the proteins differ at their C termini.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant GA Binding Protein Transcription Factor Beta (GABPb) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to GA Binding Protein Transcription Factor Beta (GABPb) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to GA Binding Protein Transcription Factor Beta (GABPb) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for GA Binding Protein Transcription Factor Beta (GABPb) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for GA Binding Protein Transcription Factor Beta (GABPb) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant GA Binding Protein Transcription Factor Beta (GABPb) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to GA Binding Protein Transcription Factor Beta (GABPb) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to GA Binding Protein Transcription Factor Beta (GABPb) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for GA Binding Protein Transcription Factor Beta (GABPb) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for GA Binding Protein Transcription Factor Beta (GABPb) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant GA Binding Protein Transcription Factor Beta (GABPb) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to GA Binding Protein Transcription Factor Beta (GABPb) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to GA Binding Protein Transcription Factor Beta (GABPb) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for GA Binding Protein Transcription Factor Beta (GABPb) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for GA Binding Protein Transcription Factor Beta (GABPb) | ELISA Kit Customized Service Offer |
- "cDNA cloning of transcription factor E4TF1 subunits with Ets and notch motifs."Mol. Cell. Biol. 13:1385-1391(1993) [PubMed] [Europe PMC] [Abstract]
- "Four structurally distinct, non-DNA-binding subunits of human nuclear respiratory factor 2 share a conserved transcriptional activation domain."Mol. Cell. Biol. 15:102-111(1995) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Purification and characterization of nuclear factors binding to the negative regulatory element D of human apolipoprotein A-II promoter: a negative regulatory effect is reversed by GABP, an Ets-related protein."Biochemistry 33:12139-12148(1994) [PubMed] [Europe PMC] [Abstract]
- "Identity of GABP with NRF-2, a multisubunit activator of cytochrome oxidase expression, reveals a cellular role for an ETS domain activator of viral promoters."Genes Dev. 7:380-392(1993) [PubMed] [Europe PMC] [Abstract]
- "Nuclear respiratory factors 1 and 2 utilize similar glutamine-containing clusters of hydrophobic residues to activate transcription."Mol. Cell. Biol. 16:5708-5716(1996) [PubMed] [Europe PMC] [Abstract]
- "The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP."EMBO J. 19:683-690(2000) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
- "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]