N-Acylsphingosine Amidohydrolase 2C (ASAH2C)
[Edit]Non-lysosomal ceramidase C; Putative neutral ceramidase C
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Neutral ceramidase C also known as N-acylsphingosine amidohydrolase 2C or non-lysosomal ceramidase C or ASAH2C is a ceramidase enzyme encoded by the ASAH2C gene.Ceramidase is an enzyme which cleaves fatty acids from ceramide, producing sphingosine (SPH) which in turn is phosphorylated by a sphingosine kinase to form sphingosine-1-phosphate (S1P).
Ceramide, SPH, and S1P are bioactive lipids that mediate cell proliferation, differentiation, apoptosis, adhesion, and migration. Presently, 7 human ceramidases encoded by 7 distinct genes.
neutral ceramidase (ASAH2, ASAH2B, ASAH2C) – protective against inflammatory cytokines
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant N-Acylsphingosine Amidohydrolase 2C (ASAH2C) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to N-Acylsphingosine Amidohydrolase 2C (ASAH2C) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to N-Acylsphingosine Amidohydrolase 2C (ASAH2C) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for N-Acylsphingosine Amidohydrolase 2C (ASAH2C) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for N-Acylsphingosine Amidohydrolase 2C (ASAH2C) | ELISA Kit Customized Service Offer |
- "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]