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RAN Binding Protein 1 (RANBP1)

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HTF9A; Ran-Specific GTPase-Activating Protein

RAN Binding Protein 1 (RANBP1)
CCC G520
HGNC 9847
MGI 96269
PubMed 23108393
RGD 1310521
UniProt P43487
Wiki RANBP1
RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.Based on partial peptide sequence of the purified protein, primers were designed to amplify a cDNA encoding the protein. They also showed that RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAN Binding Protein 1 (RANBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAN Binding Protein 1 (RANBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAN Binding Protein 1 (RANBP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAN Binding Protein 1 (RANBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAN Binding Protein 1 (RANBP1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAN Binding Protein 1 (RANBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAN Binding Protein 1 (RANBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAN Binding Protein 1 (RANBP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAN Binding Protein 1 (RANBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAN Binding Protein 1 (RANBP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAN Binding Protein 1 (RANBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAN Binding Protein 1 (RANBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAN Binding Protein 1 (RANBP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAN Binding Protein 1 (RANBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAN Binding Protein 1 (RANBP1) ELISA Kit Customized Service Offer
  1. "Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1."EMBO J. 14:705-715(1995) [PubMed] [Europe PMC] [Abstract]
  2. "RanBP1, a Ras-like nuclear G protein binding to Ran/TC4, inhibits RCC1 via Ran/TC4."Mol. Gen. Genet. 247:661-669(1995) [PubMed] [Europe PMC] [Abstract]
  3. "A genome annotation-driven approach to cloning the human ORFeome."Genome Biol. 5:R84.1-R84.11(2004) [PubMed] [Europe PMC] [Abstract]
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  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  12. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  13. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]