Tubulointerstitial Nephritis Antigen Like Protein 1 (TINAGL1)

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ARG1; LCN7; LIECG3; AZ-1; TINAGRP; GIS5; OLRG2; TINAGL; Lipocalin 7; Adrenocortical Zonation Factor 1; Glucocorticoid-inducible protein 5; Oxidized LDL-responsive gene 2

Tubulointerstitial Nephritis Antigen Like Protein 1 (TINAGL1)
Tubulointerstitial nephritis antigen-like 1 has been cloned from mouse adrenocortical cells and is known to be closely associated with zonal differentiation of adrenocortical cells. In cell culture systems, TINAGL1 is a matricellular protein that interacts with both structural matrix proteins and cell surface receptors. However, the physiological roles of TINAGL1 and regulation of its expression are still not clearly understood.
In the present study, the expression and localization of TINAGL1 in peri-implantation mouse embryos was examined. During preimplantation, the expression of both Tinagl1 mRNA and TINAGL1 protein was increased just prior to implantation. In blastocysts, TINAGL1 expression was localized to the trophectoderm.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG483Hu01 Recombinant Tubulointerstitial Nephritis Antigen Like Protein 1 (TINAGL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG483Hu01 Polyclonal Antibody to Tubulointerstitial Nephritis Antigen Like Protein 1 (TINAGL1) WB; IHC; ICC; IP.
LAG483Hu71 Biotin-Linked Polyclonal Antibody to Tubulointerstitial Nephritis Antigen Like Protein 1 (TINAGL1) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for Tubulointerstitial Nephritis Antigen Like Protein 1 (TINAGL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tubulointerstitial Nephritis Antigen Like Protein 1 (TINAGL1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG483Mu01 Recombinant Tubulointerstitial Nephritis Antigen Like Protein 1 (TINAGL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Tubulointerstitial Nephritis Antigen Like Protein 1 (TINAGL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tubulointerstitial Nephritis Antigen Like Protein 1 (TINAGL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tubulointerstitial Nephritis Antigen Like Protein 1 (TINAGL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tubulointerstitial Nephritis Antigen Like Protein 1 (TINAGL1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tubulointerstitial Nephritis Antigen Like Protein 1 (TINAGL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tubulointerstitial Nephritis Antigen Like Protein 1 (TINAGL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tubulointerstitial Nephritis Antigen Like Protein 1 (TINAGL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tubulointerstitial Nephritis Antigen Like Protein 1 (TINAGL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tubulointerstitial Nephritis Antigen Like Protein 1 (TINAGL1) ELISA Kit Customized Service Offer
  1. "Cloning, characterization, and expression of the human TIN-ag-RP gene encoding a novel putative extracellular matrix protein."Biochem. Biophys. Res. Commun. 271:474-480(2000) [PubMed] [Europe PMC] [Abstract]
  2. "TIN-ag-RP, a novel catalytically inactive cathepsin B-related protein with EGF domains, is predominantly expressed in vascular smooth muscle cells."Biochemistry 40:1350-1357(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  4. "Large-scale cDNA transfection screening for genes related to cancer development and progression." Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
  7. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  9. "Signal peptide prediction based on analysis of experimentally verified cleavage sites."Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
  10. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]