Lipidosin (LPD)
[Edit]ACSBG1; BG1; BGM; GR-LACS; hBG1; hsBG; Bubblegum; Very Long-Chain Acyl-CoA Synthetase; Acyl Coenzyme A Synthetase Bubblegum Family, Member 1
-96353.jpg)
ACSBG1 possesses long-chain acyl-CoA synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis.The sequence BAA31606.2 differs from that shown. Reason: Erroneous initiation.
Expressed primarily in brain. Expressed at lower level in testis and adrenal gland. Present in all regions of brain except pituitary.Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Lipidosin (LPD) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Lipidosin (LPD) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Lipidosin (LPD) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Lipidosin (LPD) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Lipidosin (LPD) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPG353Mu01 | Recombinant Lipidosin (LPD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | n/a | Monoclonal Antibody to Lipidosin (LPD) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Lipidosin (LPD) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Lipidosin (LPD) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Lipidosin (LPD) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Lipidosin (LPD) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Lipidosin (LPD) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Lipidosin (LPD) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Lipidosin (LPD) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Lipidosin (LPD) | ELISA Kit Customized Service Offer |
- "Very long-chain acyl-CoA synthetases. Human 'bubblegum' represents a new family of proteins capable of activating very long-chain fatty acids."J. Biol. Chem. 275:35162-35169(2000) [PubMed] [Europe PMC] [Abstract]
- "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."DNA Res. 5:169-176(1998) [PubMed] [Europe PMC] [Abstract]
- "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "Analysis of the DNA sequence and duplication history of human chromosome 15." Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "The acyl-CoA synthetase 'bubblegum' (lipidosin): further characterization and role in neuronal fatty acid beta-oxidation."J. Biol. Chem. 278:47070-47078(2003) [PubMed] [Europe PMC] [Abstract]