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Acyl Coenzyme A Synthetase Family, Member 2 (ACSF2)

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ACSMW; Acyl-CoA synthetase family member 2, mitochondrial

Acyl Coenzyme A Synthetase Family, Member 2 (ACSF2)
CCC G351
HGNC 26101
MGI 2388287
PubMed 24104204
RGD 1562656
UniProt Q96CM8
Fatty acids are incorporated into membranes and signaling molecules and have roles in energy storage and metabolism. These essential functions require activation of the fatty acid by acyl-coenzyme A (CoA) synthetases, such as ACSF2, which form an activating thioester linkage between the fatty acid and CoA.The deduced 615-amino acid protein contains all 5 motifs characteristic of acyl-CoA synthetases. Phylogenetic analysis revealed that ACSF2 belongs to a small group of acyl-CoA synthetases that differ significantly from all other clades of acyl-CoA synthetases and from each other. FLJ20920 contains a PPARG-recognition element in its promoter sequence. Transfection of antisense FLJ20920 into preadipocytes resulted in decreased triglyceride accumulation and reduced expression of GLUT4 (SLC2A4) and HSL (LIPE) mRNA.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG351Hu01 Recombinant Acyl Coenzyme A Synthetase Family, Member 2 (ACSF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Acyl Coenzyme A Synthetase Family, Member 2 (ACSF2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Acyl Coenzyme A Synthetase Family, Member 2 (ACSF2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Acyl Coenzyme A Synthetase Family, Member 2 (ACSF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acyl Coenzyme A Synthetase Family, Member 2 (ACSF2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Acyl Coenzyme A Synthetase Family, Member 2 (ACSF2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Acyl Coenzyme A Synthetase Family, Member 2 (ACSF2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Acyl Coenzyme A Synthetase Family, Member 2 (ACSF2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Acyl Coenzyme A Synthetase Family, Member 2 (ACSF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acyl Coenzyme A Synthetase Family, Member 2 (ACSF2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG351Ra01 Recombinant Acyl Coenzyme A Synthetase Family, Member 2 (ACSF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Acyl Coenzyme A Synthetase Family, Member 2 (ACSF2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Acyl Coenzyme A Synthetase Family, Member 2 (ACSF2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Acyl Coenzyme A Synthetase Family, Member 2 (ACSF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acyl Coenzyme A Synthetase Family, Member 2 (ACSF2) ELISA Kit Customized Service Offer
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  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Identification of novel PPARgamma target genes in primary human adipocytes."Gene 369:90-99(2006) [PubMed] [Europe PMC] [Abstract]
  6. "Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome."J. Lipid Res. 48:2736-2750(2007) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]