Thymus Specific Serine Protease (TSSP)

[Edit]

PRSS16; Protease,Serine 16

Thymus Specific Serine Protease (TSSP)
TSSP is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined.The deduced 514-amino acid PRSS16 protein, which the authors termed TSSP, has a calculated molecular mass of 55 kD. PRSS16 contains a putative N-terminal signal peptide and a prolylendopeptidase consensus sequence. Within its 3-prime untranslated region, it has 2 different polyadenylation sites. PRSS16 shares sequence similarity with prolylcarboxypeptidase (PRCP), particularly around the active-site serine.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG320Hu01 Recombinant Thymus Specific Serine Protease (TSSP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG320Hu01 Polyclonal Antibody to Thymus Specific Serine Protease (TSSP) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Thymus Specific Serine Protease (TSSP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thymus Specific Serine Protease (TSSP) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Thymus Specific Serine Protease (TSSP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Thymus Specific Serine Protease (TSSP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Thymus Specific Serine Protease (TSSP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Thymus Specific Serine Protease (TSSP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thymus Specific Serine Protease (TSSP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG320Ra01 Recombinant Thymus Specific Serine Protease (TSSP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Thymus Specific Serine Protease (TSSP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Thymus Specific Serine Protease (TSSP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Thymus Specific Serine Protease (TSSP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thymus Specific Serine Protease (TSSP) ELISA Kit Customized Service Offer
  1. "Cloning of a novel MHC-encoded serine peptidase highly expressed by cortical epithelial cells of the thymus."Cell. Immunol. 196:80-86(1999) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]