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Far Upstream Element Binding Protein 3 (FUBP3)

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FBP3

Far Upstream Element Binding Protein 3 (FUBP3)
CCC G312
HGNC 4005
MGI 2443699
PubMed 21252297
RGD 1307004
UniProt Q96I24
The far upstream element (FUSE)-binding protein FBP1 (FUBP1) binds to the FUSE of the human MYC protooncogene. Davis-Smyth et al. (1996) isolated cDNAs encoding FBP2 (KHSRP) and FBP3. Like FBP1 and FBP2, the predicted 600-amino acid FBP3 protein contains 3 distinct domains.
The central nucleic acid-binding region contains 4 regularly spaced alternating units, each consisting of a KH motif and an amphipathic helix. Expression studies in mammalian cells indicated that the C-terminal domains of the FBPs are potent transcriptional activators. The FBPs bound specifically to 1 strand of the FUSE in vitro. Northern blot analysis revealed that FBP3 was expressed as a 3.4-kb mRNA in all cells and tissues tested.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG312Hu01 Recombinant Far Upstream Element Binding Protein 3 (FUBP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Far Upstream Element Binding Protein 3 (FUBP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Far Upstream Element Binding Protein 3 (FUBP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Far Upstream Element Binding Protein 3 (FUBP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Far Upstream Element Binding Protein 3 (FUBP3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG312Mu01 Recombinant Far Upstream Element Binding Protein 3 (FUBP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG312Mu01 Polyclonal Antibody to Far Upstream Element Binding Protein 3 (FUBP3) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Far Upstream Element Binding Protein 3 (FUBP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Far Upstream Element Binding Protein 3 (FUBP3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Far Upstream Element Binding Protein 3 (FUBP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Far Upstream Element Binding Protein 3 (FUBP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Far Upstream Element Binding Protein 3 (FUBP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Far Upstream Element Binding Protein 3 (FUBP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Far Upstream Element Binding Protein 3 (FUBP3) ELISA Kit Customized Service Offer
  1. "The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators."J. Biol. Chem. 271:31679-31687(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]