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Proteasome 26S Subunit, ATPase 6 (PSMC6)

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CADP44; P44; SUG2; p42; 26S proteasome AAA-ATPase subunit RPT4; Proteasome 26S subunit ATPase 6; Proteasome subunit p42

Proteasome 26S Subunit, ATPase 6 (PSMC6)
CCC G276
HGNC 9553
MGI 1914339
PubMed 21944250
RGD 1308825
UniProt P62333
Wiki PSMC6
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
PSMC6 encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG276Hu01 Recombinant Proteasome 26S Subunit, ATPase 6 (PSMC6) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG276Hu01 Polyclonal Antibody to Proteasome 26S Subunit, ATPase 6 (PSMC6) WB; IHC; ICC; IP.
Assay Kits SEG276Hu ELISA Kit for Proteasome 26S Subunit, ATPase 6 (PSMC6) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Proteasome 26S Subunit, ATPase 6 (PSMC6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Proteasome 26S Subunit, ATPase 6 (PSMC6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Proteasome 26S Subunit, ATPase 6 (PSMC6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Proteasome 26S Subunit, ATPase 6 (PSMC6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Proteasome 26S Subunit, ATPase 6 (PSMC6) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Proteasome 26S Subunit, ATPase 6 (PSMC6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Proteasome 26S Subunit, ATPase 6 (PSMC6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Proteasome 26S Subunit, ATPase 6 (PSMC6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Proteasome 26S Subunit, ATPase 6 (PSMC6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Proteasome 26S Subunit, ATPase 6 (PSMC6) ELISA Kit Customized Service Offer
  1. "cDNA cloning of p42, a shared subunit of two proteasome regulatory proteins, reveals a novel member of the AAA protein family."FEBS Lett. 387:184-188(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Identification, purification, and characterization of a PA700-dependent activator of the proteasome."J. Biol. Chem. 271:3112-3118(1996) [PubMed] [Europe PMC] [Abstract]
  5. "Proteasomal ATPase-associated factor 1 negatively regulates proteasome activity by interacting with proteasomal ATPases."Mol. Cell. Biol. 25:3842-3853(2005) [PubMed] [Europe PMC] [Abstract]
  6. "Mass spectrometric characterization of the affinity-purified human 26S proteasome complex."Biochemistry 46:3553-3565(2007) [PubMed] [Europe PMC] [Abstract]
  7. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]