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Stromal Antigen 3 (STAG3)

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SCC3 homolog 3; Stromalin-3; Cohesin subunit SA-3

Stromal Antigen 3 (STAG3)
CCC G203
HGNC 11356
MGI 1355311
PubMed 19270026
RGD 621333
UniProt Q9UJ98
Wiki STAG3
STAG3 cDNAs encoding deduced proteins of 1,225 and 1,240 amino acids, respectively. Human STAG3 shares 75% sequence identity with the mouse Stag3 protein and approximately 45% similarity with human STAG1 and STAG2.
STAG3 contains an acidic C-terminal domain, a 28-amino acid domain conserved among mammalian stromalins, and an 86-amino acid domain, designated SCD, conserved among all stromalin family members. Northern blot analysis of human tissues revealed testis-specific expression of a 4.5-kb STAG3 transcript. In mouse tissues, the highest level of expression was found in male germ cells undergoing the first meiotic division.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG203Hu01 Recombinant Stromal Antigen 3 (STAG3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Stromal Antigen 3 (STAG3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Stromal Antigen 3 (STAG3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Stromal Antigen 3 (STAG3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Stromal Antigen 3 (STAG3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Stromal Antigen 3 (STAG3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Stromal Antigen 3 (STAG3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Stromal Antigen 3 (STAG3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Stromal Antigen 3 (STAG3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Stromal Antigen 3 (STAG3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Stromal Antigen 3 (STAG3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Stromal Antigen 3 (STAG3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Stromal Antigen 3 (STAG3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Stromal Antigen 3 (STAG3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Stromal Antigen 3 (STAG3) ELISA Kit Customized Service Offer
  1. "STAG3, a novel gene encoding a protein involved in meiotic chromosome pairing and location of STAG3-related genes flanking the Williams-Beuren syndrome deletion."FASEB J. 14:581-592(2000) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "STAG2 and Rad21 mammalian mitotic cohesins are implicated in meiosis."EMBO Rep. 3:543-550(2002) [PubMed] [Europe PMC] [Abstract]
  7. "Genome-wide linkage in a highly consanguineous pedigree reveals two novel loci on chromosome 7 for non-syndromic familial Premature Ovarian Failure."PLoS ONE 7:E33412-E33412(2012) [PubMed] [Europe PMC] [Abstract]
  8. "Mutant cohesin in premature ovarian failure."N. Engl. J. Med. 370:943-949(2014) [PubMed] [Europe PMC] [Abstract]