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Epithelial Stromal Interaction 1, Breast (EPSTI1)

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BRESI1; Epithelial-stromal interaction protein 1

Epithelial Stromal Interaction 1, Breast (EPSTI1)
CCC G200
HGNC 16465
MGI 1915168
PubMed 20133812
RGD 1563207
UniProt Q96J88
By differential display, Nielsen et al. (2002) identified EPSTI1 as a transcript that is induced by coculture of breast tumor cells and fibroblasts, and they generated the full-length cDNA by 5-prime RACE of normal breast or placenta RNA. The deduced 307-amino acid protein has a calculated molecular mass of about 35 kD. It contains no N-terminal signal sequence and no transmembrane domains; however, there are 3 coiled-coil regions. Northern blot analysis revealed a transcript size of 1.5 kb. Real-time PCR revealed highest expression in placenta; strong expression in small intestine, spleen, salivary gland, and testes; and low levels of expression in normal breast and several other tissues. The expression of EPSTI1 was upregulated up to 72 times (range 5.6-72.1) in all 14 breast carcinomas tested.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG200Hu01 Recombinant Epithelial Stromal Interaction 1, Breast (EPSTI1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG200Hu01 Polyclonal Antibody to Epithelial Stromal Interaction 1, Breast (EPSTI1) WB
MAG200Hu21 Monoclonal Antibody to Epithelial Stromal Interaction 1, Breast (EPSTI1) WB; IHC; ICC; IP.
Assay Kits SEG200Hu ELISA Kit for Epithelial Stromal Interaction 1, Breast (EPSTI1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Epithelial Stromal Interaction 1, Breast (EPSTI1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Epithelial Stromal Interaction 1, Breast (EPSTI1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Epithelial Stromal Interaction 1, Breast (EPSTI1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Epithelial Stromal Interaction 1, Breast (EPSTI1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Epithelial Stromal Interaction 1, Breast (EPSTI1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Epithelial Stromal Interaction 1, Breast (EPSTI1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Epithelial Stromal Interaction 1, Breast (EPSTI1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Epithelial Stromal Interaction 1, Breast (EPSTI1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Epithelial Stromal Interaction 1, Breast (EPSTI1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Epithelial Stromal Interaction 1, Breast (EPSTI1) ELISA Kit Customized Service Offer
  1. "Identification of EPSTI1, a novel gene induced by epithelial-stromal interaction in human breast cancer."Genomics 79:703-710(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and analysis of human chromosome 13." Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Isolation and expression profiling of genes upregulated in the peripheral blood cells of systemic lupus erythematosus patients."DNA Res. 12:429-439(2005) [PubMed] [Europe PMC] [Abstract]