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Oxoglutarate Dehydrogenase (OGDH)

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AKGDH; E1k; OGDC; Alpha-Ketoglutarate Dehydrogenase,Lipoamide; 2-Oxoglutarate Dehydrogenase E1 Component,Mitochondrial

Oxoglutarate Dehydrogenase (OGDH)
CCC G187
HGNC 8124
MGI 1098267
PubMed 1542694
RGD 1561359
UniProt Q02218
Wiki OGDH
Oxoglutarate Dehydrogenase is one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG187Hu01 Recombinant Oxoglutarate Dehydrogenase (OGDH) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG187Hu01 Polyclonal Antibody to Oxoglutarate Dehydrogenase (OGDH) WB; IHC; ICC; IP.
MAG187Hu21 Monoclonal Antibody to Oxoglutarate Dehydrogenase (OGDH) WB; IHC; ICC; IP.
Assay Kits SEG187Hu ELISA Kit for Oxoglutarate Dehydrogenase (OGDH) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Oxoglutarate Dehydrogenase (OGDH) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Oxoglutarate Dehydrogenase (OGDH) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Oxoglutarate Dehydrogenase (OGDH) Polyclonal Antibody Customized Service Offer
Assay Kits SEG187Mu ELISA Kit for Oxoglutarate Dehydrogenase (OGDH) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG187Ra01 Recombinant Oxoglutarate Dehydrogenase (OGDH) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAG187Ra21 Monoclonal Antibody to Oxoglutarate Dehydrogenase (OGDH) WB; IHC; ICC; IP.
PAG187Ra01 Polyclonal Antibody to Oxoglutarate Dehydrogenase (OGDH) WB; IHC; ICC; IP.
Assay Kits SEG187Ra ELISA Kit for Oxoglutarate Dehydrogenase (OGDH) Enzyme-linked immunosorbent assay for Antigen Detection.
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