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Cysteinyl tRNA Synthetase (CARS)

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CARS1; CysRS; Cysteine tRNA Ligase 1,Cytoplasmic; Cysteinyl-tRNA synthetase

Cysteinyl tRNA Synthetase (CARS)
CCC G144
HGNC 1493
MGI 1351477
RGD 1310747
UniProt Q5HYE4
Cysteinyl-tRNA Synthetase isa class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid.
This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cysteinyl tRNA Synthetase (CARS) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cysteinyl tRNA Synthetase (CARS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cysteinyl tRNA Synthetase (CARS) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cysteinyl tRNA Synthetase (CARS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cysteinyl tRNA Synthetase (CARS) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG144Mu01 Recombinant Cysteinyl tRNA Synthetase (CARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Cysteinyl tRNA Synthetase (CARS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cysteinyl tRNA Synthetase (CARS) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cysteinyl tRNA Synthetase (CARS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cysteinyl tRNA Synthetase (CARS) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cysteinyl tRNA Synthetase (CARS) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cysteinyl tRNA Synthetase (CARS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cysteinyl tRNA Synthetase (CARS) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cysteinyl tRNA Synthetase (CARS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cysteinyl tRNA Synthetase (CARS) ELISA Kit Customized Service Offer
  1. "Nucleotide and deduced amino acid sequence of human cysteinyl-tRNA synthetase."DNA Seq. 4:243-248(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Isolation of two cDNAs encoding functional human cytoplasmic cysteinyl-tRNA synthetase."Biol. Chem. 382:399-406(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  5. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor."Genes Chromosomes Cancer 34:354-362(2002) [PubMed] [Europe PMC] [Abstract]
  8. "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."Nat. Biotechnol. 23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
  9. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  10. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  14. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]