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Seryl tRNA Synthetase (SARS)

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SERS; SerRS; Serine tRNA Ligase 1,Cytoplasmic; Seryl-tRNA(Ser/Sec) synthetase

Seryl tRNA Synthetase (SARS)
CCC G142
HGNC 10537
MGI 102809
PubMed 21255763
RGD 628813
UniProt P49591
Wiki SARS
Vincent et al. (1997) assembled 2 overlapping clones of SARS, which they called SERS, isolated from human fetal and infant brain cDNA libraries. They obtained the full-length cDNA by 5-prime RACE of a brain cDNA library.
The deduced 514-amino acid protein has a calculated molecular mass of about 59 kD. SARS has a 2-domain structure consisting of a tRNA-binding domain and a catalytic domain, which contains the 3 motifs shared by class II aminoacyl-tRNA synthetases. Motifs 2 and 3 share sequence conservation between prokaryotic and eukaryotic seryl-tRNA synthetases. SARS has no mitochondrial import signal sequence. Partial Sars protein sequences from mouse and Chinese hamster share 94% and 92% identity with human SARS

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Seryl tRNA Synthetase (SARS) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Seryl tRNA Synthetase (SARS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Seryl tRNA Synthetase (SARS) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Seryl tRNA Synthetase (SARS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Seryl tRNA Synthetase (SARS) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Seryl tRNA Synthetase (SARS) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Seryl tRNA Synthetase (SARS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Seryl tRNA Synthetase (SARS) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Seryl tRNA Synthetase (SARS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Seryl tRNA Synthetase (SARS) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Seryl tRNA Synthetase (SARS) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Seryl tRNA Synthetase (SARS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Seryl tRNA Synthetase (SARS) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Seryl tRNA Synthetase (SARS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Seryl tRNA Synthetase (SARS) ELISA Kit Customized Service Offer
  1. "Genomic organization, cDNA sequence, bacterial expression, and purification of human seryl-tRNA synthase."Eur. J. Biochem. 250:77-84(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]