Synergin Gamma (SYNRg)

[Edit]

AP1GBP1; SYNG; Adaptor-Related Protein Complex 1 Gamma Subunit-Binding Protein 1

Synergin Gamma (SYNRg)
AP1 subunit gamma-binding protein 1 is a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene. Northern blot analysis of multiple rat tissues revealed ubiquitous expression of Ap1gbp1 transcripts of 4.4 to 5.6 kb. Western blot analysis of rat tissues detected 110- and 150-kD bands in brain and a single 190-kD band in liver. Immunofluorescence localization in Madin Darby bovine kidney cells showed colocalization of AP1GBP1 with gamma-adaptin within the TGN and in the cytosol.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG120Hu01 Recombinant Synergin Gamma (SYNRg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAG120Hu21 Monoclonal Antibody to Synergin Gamma (SYNRg) WB; IHC; ICC; IP.
PAG120Hu01 Polyclonal Antibody to Synergin Gamma (SYNRg) WB; IHC; ICC; IP.
Assay Kits SEG120Hu ELISA Kit for Synergin Gamma (SYNRg) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Synergin Gamma (SYNRg) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Synergin Gamma (SYNRg) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Synergin Gamma (SYNRg) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Synergin Gamma (SYNRg) CLIA Kit Customized Service Offer
n/a ELISA Kit for Synergin Gamma (SYNRg) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Synergin Gamma (SYNRg) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Synergin Gamma (SYNRg) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Synergin Gamma (SYNRg) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Synergin Gamma (SYNRg) CLIA Kit Customized Service Offer
n/a ELISA Kit for Synergin Gamma (SYNRg) ELISA Kit Customized Service Offer
  1. "Gamma-synergin: an EH domain-containing protein that interacts with gamma-adaptin."J. Cell Biol. 146:993-1004(1999) [PubMed] [Europe PMC] [Abstract]
  2. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Adaptor gamma ear homology domain conserved in gamma-adaptin and GGA proteins that interact with gamma-synergin."Biochem. Biophys. Res. Commun. 271:719-725(2000) [PubMed] [Europe PMC] [Abstract]
  6. "EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking."J. Cell Biol. 160:213-222(2003) [PubMed] [Europe PMC] [Abstract]
  7. "Phosphoproteome of resting human platelets."J. Proteome Res. 7:526-534(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  9. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  10. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Large-scale proteomics analysis of the human kinome."Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  13. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  14. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  15. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  16. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  17. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]