Purinergic Receptor P2X, Ligand Gated Ion Channel 4 (P2RX4)

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P2X4; P2X4R; P2X Purinoceptor 4; ATP receptor; Purinergic receptor

Purinergic Receptor P2X, Ligand Gated Ion Channel 4 (P2RX4)
P2X purinoceptor 4 is a protein belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants have been identified for this gene although their full-length natures have not been determined.
P2X4 expression was nearly undetectable in promyelocytes and after granulocyte differentiation. During monocytic differentiation, P2X4 was highly expressed, showing a biphasic peak in early and later stages of differentiation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG074Hu01 Recombinant Purinergic Receptor P2X, Ligand Gated Ion Channel 4 (P2RX4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG074Hu01 Polyclonal Antibody to Purinergic Receptor P2X, Ligand Gated Ion Channel 4 (P2RX4) WB; IHC; ICC; IP.
Assay Kits SEG074Hu ELISA Kit for Purinergic Receptor P2X, Ligand Gated Ion Channel 4 (P2RX4) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG074Mu01 Recombinant Purinergic Receptor P2X, Ligand Gated Ion Channel 4 (P2RX4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Purinergic Receptor P2X, Ligand Gated Ion Channel 4 (P2RX4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Purinergic Receptor P2X, Ligand Gated Ion Channel 4 (P2RX4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Purinergic Receptor P2X, Ligand Gated Ion Channel 4 (P2RX4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Purinergic Receptor P2X, Ligand Gated Ion Channel 4 (P2RX4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Purinergic Receptor P2X, Ligand Gated Ion Channel 4 (P2RX4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Purinergic Receptor P2X, Ligand Gated Ion Channel 4 (P2RX4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Purinergic Receptor P2X, Ligand Gated Ion Channel 4 (P2RX4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Purinergic Receptor P2X, Ligand Gated Ion Channel 4 (P2RX4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Purinergic Receptor P2X, Ligand Gated Ion Channel 4 (P2RX4) ELISA Kit Customized Service Offer
  1. "Characterization of recombinant human P2X4 receptor reveals pharmacological differences to the rat homologue."Mol. Pharmacol. 51:109-118(1997) [PubMed] [Europe PMC] [Abstract]
  2. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Site-specific splice variation of the human P2X4 receptor."Neurosci. Lett. 273:183-186(1999) [PubMed] [Europe PMC] [Abstract]
  5. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]