Pancreatic Polypeptide Receptor 1 (PPYR1)
[Edit]PP1; NPY4-R; NPY4R; Y4; Neuropeptide Y Receptor Type 4
![Pancreatic Polypeptide Receptor 1 (PPYR1)](/upload/item/img/Pancreatic-Polypeptide-Receptor-1-(PPYR1)-96036.jpg)
Pancreatic polypeptide (PP), neuropeptide Y (NPY), and peptide YY (PYY) are related 36-amino acid hormones. A number of structurally related receptors for these peptides have been isolated. Bard et al. (1995) used the rat Y1 receptor (NPY1R) as a probe to clone a novel receptor, PPYR1 (termed Y4 by them), from a human genomic DNA library. PPYR1 encodes a predicted 375-amino acid polypeptide having highest homology to the Y1 receptor gene (42% amino acid identity). Using RT-PCR, they showed that the PPYR1 receptor is expressed in several human tissues, including brain, coronary artery, and ileum.Bard et al. (1995) expressed the PPYR1 gene in COS-7 cells and performed a hormone-binding assay which showed that the PPYR1 receptor binds PP, PYY, and NPY hormones.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Pancreatic Polypeptide Receptor 1 (PPYR1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Pancreatic Polypeptide Receptor 1 (PPYR1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Pancreatic Polypeptide Receptor 1 (PPYR1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Pancreatic Polypeptide Receptor 1 (PPYR1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Pancreatic Polypeptide Receptor 1 (PPYR1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Pancreatic Polypeptide Receptor 1 (PPYR1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Pancreatic Polypeptide Receptor 1 (PPYR1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Pancreatic Polypeptide Receptor 1 (PPYR1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Pancreatic Polypeptide Receptor 1 (PPYR1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Pancreatic Polypeptide Receptor 1 (PPYR1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Pancreatic Polypeptide Receptor 1 (PPYR1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Pancreatic Polypeptide Receptor 1 (PPYR1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Pancreatic Polypeptide Receptor 1 (PPYR1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Pancreatic Polypeptide Receptor 1 (PPYR1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Pancreatic Polypeptide Receptor 1 (PPYR1) | ELISA Kit Customized Service Offer |
- "Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y, and peptide YY."J. Biol. Chem. 270:26762-26765(1995) [PubMed] [Europe PMC] [Abstract]
- "Cloning of a human receptor of the NPY receptor family with high affinity for pancreatic polypeptide and peptide YY."J. Biol. Chem. 270:29123-29128(1995) [PubMed] [Europe PMC] [Abstract]
- "Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors."Proc. Natl. Acad. Sci. U.S.A. 93:4661-4665(1996) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]