≡

Sperm Associated Antigen 7 (SPAG7)

[Edit]

ACRP; FSA-1

Sperm Associated Antigen 7 (SPAG7)
CCC F907
HGNC 11216
MGI 107380
PubMed 24452265
RGD 1305473
UniProt O75391
Wiki SPAG7
By sequencing cDNAs obtained from umbilical cord blood CD34-positive hematopoietic stem/progenitor cells, Mao et al. (1998) identified SPAG7, a homolog of fox sperm acrosomal protein-1 (Fsa1). The deduced protein contains 293 amino acids.The International Radiation Hybrid Mapping Consortium mapped the SPAG7 gene to chromosome 17 (WI-8402).The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sperm Associated Antigen 7 (SPAG7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sperm Associated Antigen 7 (SPAG7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sperm Associated Antigen 7 (SPAG7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sperm Associated Antigen 7 (SPAG7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sperm Associated Antigen 7 (SPAG7) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sperm Associated Antigen 7 (SPAG7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sperm Associated Antigen 7 (SPAG7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sperm Associated Antigen 7 (SPAG7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sperm Associated Antigen 7 (SPAG7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sperm Associated Antigen 7 (SPAG7) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sperm Associated Antigen 7 (SPAG7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sperm Associated Antigen 7 (SPAG7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sperm Associated Antigen 7 (SPAG7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sperm Associated Antigen 7 (SPAG7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sperm Associated Antigen 7 (SPAG7) ELISA Kit Customized Service Offer
  1. "Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning."Proc. Natl. Acad. Sci. U.S.A. 95:8175-8180(1998) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Cloning and characterization of a fox sperm protein FSA-1."Reprod. Fertil. Dev. 6:761-770(1994) [PubMed] [Europe PMC] [Abstract]
  4. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  5. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  6. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
  9. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  10. "Solution structure of the R3H domain of human sperm-associated antigen 7."Submitted (NOV-2005) to the PDB data bank