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Septin 2 (SEPT2)

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DIFF6; NEDD5; hNedd5; Pnutl3; Neural Precursor Cell Expressed,Developmentally Down-Regulated 5

Septin 2 (SEPT2)
CCC F875
HGNC 7729
MGI 97298
PubMed 8697812
RGD 620056
UniProt Q15019
Wiki SEPT2
SEPT2 can hetero-oligomerize wth SEPT6 and SEPT7 to form filaments. SEPT2 interacted with SEPT6 through its C-terminal coiled-coil domain. Knockdown of SEPT2, SEPT6, and SEPT7 in causes actin stress fibers to disintegrate and cells to lose polarity. The NEDD5 cDNA encodes a predicted protein of 406 amino acids. The deduced peptide sequence contains conserved domains rich in basic residues, a motif of the GTPase superfamily. Different poly(A) sites account for generation of 2 transcripts. The major 3.5-kb transcript was expressed ubiquitously in all human tissues examined, and a 2.0-kb alternative transcript lacking any long AU-rich element in the 3-prime noncoding region was expressed abundantly only in testis, heart, and skeletal muscle.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Septin 2 (SEPT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Septin 2 (SEPT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Septin 2 (SEPT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Septin 2 (SEPT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Septin 2 (SEPT2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Septin 2 (SEPT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Septin 2 (SEPT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Septin 2 (SEPT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Septin 2 (SEPT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Septin 2 (SEPT2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Septin 2 (SEPT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Septin 2 (SEPT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Septin 2 (SEPT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Septin 2 (SEPT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Septin 2 (SEPT2) ELISA Kit Customized Service Offer
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  31. "Human septin 2 in complex with GDP."Submitted (AUG-2007) to the PDB data bank