≡

Septin 8 (SEPT8)

[Edit]

Septin 8 (SEPT8)
CCC F868
HGNC 16511
MGI 894310
PubMed 15116257
RGD 1308449
UniProt Q92599
Wiki SEPT8
SEPT8 is a member of the highly conserved septin family. Septins are 40- to 60-kD GTPases that assemble as filamentous scaffolds. They are involved in the organization of submembranous structures, in neuronal polarity, and in vesicle trafficking.
A conserved region found in all 3 variants contains the GTP-binding motif and is encoded by exons 3 through 10. Northern blot analysis detected expression of most SEPT8 variants in all brain and cardiovascular regions tested, as well as in prostate, testis, and ovary. Expression was highest in brain and aorta, and expression of each variant was tissue specific. Western blot analysis detected variant 1 at an apparent molecular mass of 58 kD in prostate, testis, and ovary.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Septin 8 (SEPT8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Septin 8 (SEPT8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Septin 8 (SEPT8) Polyclonal Antibody Customized Service Offer
Assay Kits SEF868Hu ELISA Kit for Septin 8 (SEPT8) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Septin 8 (SEPT8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Septin 8 (SEPT8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Septin 8 (SEPT8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Septin 8 (SEPT8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Septin 8 (SEPT8) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Septin 8 (SEPT8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Septin 8 (SEPT8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Septin 8 (SEPT8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Septin 8 (SEPT8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Septin 8 (SEPT8) ELISA Kit Customized Service Offer
  1. "Human septin-septin interaction: CDCrel-1 partners with KIAA0202."FEBS Lett. 519:169-172(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Isolation of new splice isoforms, characterization and expression analysis of the human septin SEPT8 (KIAA0202)."Gene 312:313-320(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain."DNA Res. 3:321-329(1996) [PubMed] [Europe PMC] [Abstract]
  4. "Identification of 40 genes on a 1-Mb contig around the IL-4 cytokine family gene cluster on mouse chromosome 11."Genomics 63:354-373(2000) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Mammalian septins nomenclature." Mol. Biol. Cell 13:4111-4113(2002) [PubMed] [Europe PMC] [Abstract]
  9. "KIAA0202, a human septin family member, interacting with hPFTAIRE1."Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao 34:520-525(2002) [PubMed] [Europe PMC] [Abstract]
  10. "The novel human platelet septin SEPT8 is an interaction partner of SEPT4."Thromb. Haemost. 91:959-966(2004) [PubMed] [Europe PMC] [Abstract]
  11. "Expression profiling the human septin gene family."J. Pathol. 206:269-278(2005) [PubMed] [Europe PMC] [Abstract]
  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  14. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]