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Septin 5 (SEPT5)

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CDCREL; CDCREL-1; CDCREL1; H5; PNUTL1; Peanut-Like 1; Cell division control-related protein 1

Septin 5 (SEPT5)
CCC F865
HGNC 9164
MGI 1195461
PubMed 9385360
RGD 621763
UniProt Q99719
Wiki SEPT5
Septin-5 is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Two transcripts of this gene, a major one of 2.2 kb and a minor one of 3.5 kb, have been observed. The 2.2 kb form results from the utilization of a non-consensus polyA signal (AACAAT).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF865Hu01 Recombinant Septin 5 (SEPT5) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF865Hu01 Polyclonal Antibody to Septin 5 (SEPT5) WB; IHC; ICC/IF
MAF865Hu21 Monoclonal Antibody to Septin 5 (SEPT5) WB; IHC; ICC; IP.
Assay Kits SEF865Hu ELISA Kit for Septin 5 (SEPT5) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Septin 5 (SEPT5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Septin 5 (SEPT5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Septin 5 (SEPT5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Septin 5 (SEPT5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Septin 5 (SEPT5) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Septin 5 (SEPT5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Septin 5 (SEPT5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Septin 5 (SEPT5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Septin 5 (SEPT5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Septin 5 (SEPT5) ELISA Kit Customized Service Offer
  1. "Alternative expression of platelet glycoprotein Ib(beta) mRNA from an adjacent 5' gene with an imperfect polyadenylation signal sequence."J. Clin. Invest. 99:520-525(1997) [PubMed] [Europe PMC] [Abstract]
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  8. , Submitted (DEC-2008) to UniProtKB
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  11. "Dopamine-dependent neurodegeneration in rats induced by viral vector-mediated overexpression of the parkin target protein, CDCrel-1."Proc. Natl. Acad. Sci. U.S.A. 100:12438-12443(2003) [PubMed] [Europe PMC] [Abstract]
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  13. "Phosphoproteome of resting human platelets."J. Proteome Res. 7:526-534(2008) [PubMed] [Europe PMC] [Abstract]
  14. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  15. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]