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Transient Receptor Potential Cation Channel Subfamily V, Member 5 (TRPV5)

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CAT2; ECAC1; OTRPC3; Epithelial Calcium Channel 1; Calcium transport protein 2; Epithelial calcium channel 1; Osm-9-like TRP channel 3

Transient Receptor Potential Cation Channel Subfamily V, Member 5 (TRPV5)
CCC F850
HGNC 3145
MGI 2429764
PubMed 23970553
RGD 620636
UniProt Q9NQA5
Wiki TRPV5
TRPV5 is mainly expressed in kidney epithelial cells, where it plays an important role in the reabsorption of Ca2+. Genetic deletion of TRPV5 in mice leads to Ca2+ loss in the urine, and consquentual hyperparathyroidism, and bone loss..
This gene is a member of the transient receptor family and the TRPV subfamily. The calcium-selective channel , TRPV5, encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 5 (TRPV5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 5 (TRPV5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 5 (TRPV5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 5 (TRPV5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 5 (TRPV5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 5 (TRPV5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 5 (TRPV5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 5 (TRPV5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 5 (TRPV5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 5 (TRPV5) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 5 (TRPV5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 5 (TRPV5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 5 (TRPV5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 5 (TRPV5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 5 (TRPV5) ELISA Kit Customized Service Offer
  1. "Molecular cloning, tissue distribution, and chromosomal mapping of the human epithelial calcium channel (ECAC1)."Genomics 67:48-53(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Structural conservation of the genes encoding CaT1, CaT2, and related cation channels."Genomics 76:99-109(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  4. "Human chromosome 7: DNA sequence and biology." Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "WNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathway."Am. J. Physiol. 295:F1472-F1484(2008) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]