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Tumor Necrosis Factor Alpha Induced Protein 1 (TNFaIP1)

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B61; B12; BACURD2; EDP1; Tumor necrosis factor, alpha-induced protein 1, endothelial; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

Tumor Necrosis Factor Alpha Induced Protein 1 (TNFaIP1)
CCC F803
HGNC 11894
MGI 104961
PubMed 23242208
RGD 3877
UniProt Q13829
Wiki TNFAIP1
TNFAIP1 was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner.
Wolf et al. (1992) characterized a novel cDNA by differential screening of a tumor necrosis factor-alpha (TNFA)-stimulated umbilical vein endothelial cell library.The protein product is involved in the primary response of the endothelium to TNF. The 3.5-kb transcript was found to be expressed in a developmentally regulated, tissue-specific manner. The gene, present in single copy, was located in the 17q22-q23 region by in situ hybridization.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tumor Necrosis Factor Alpha Induced Protein 1 (TNFaIP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tumor Necrosis Factor Alpha Induced Protein 1 (TNFaIP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tumor Necrosis Factor Alpha Induced Protein 1 (TNFaIP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tumor Necrosis Factor Alpha Induced Protein 1 (TNFaIP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Necrosis Factor Alpha Induced Protein 1 (TNFaIP1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tumor Necrosis Factor Alpha Induced Protein 1 (TNFaIP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tumor Necrosis Factor Alpha Induced Protein 1 (TNFaIP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tumor Necrosis Factor Alpha Induced Protein 1 (TNFaIP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tumor Necrosis Factor Alpha Induced Protein 1 (TNFaIP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Necrosis Factor Alpha Induced Protein 1 (TNFaIP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tumor Necrosis Factor Alpha Induced Protein 1 (TNFaIP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tumor Necrosis Factor Alpha Induced Protein 1 (TNFaIP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tumor Necrosis Factor Alpha Induced Protein 1 (TNFaIP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tumor Necrosis Factor Alpha Induced Protein 1 (TNFaIP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Necrosis Factor Alpha Induced Protein 1 (TNFaIP1) ELISA Kit Customized Service Offer
  1. "Characterization of a novel tumor necrosis factor-alpha-induced endothelial primary response gene."J. Biol. Chem. 267:1317-1326(1992) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "RhoB induces apoptosis via direct interaction with TNFAIP1 in HeLa cells."Int. J. Cancer 125:2520-2527(2009) [PubMed] [Europe PMC] [Abstract]
  7. "CK2 phosphorylates TNFAIP1 to affect its subcellular localization and interaction with PCNA."Mol. Biol. Rep. 37:2967-2973(2010) [PubMed] [Europe PMC] [Abstract]
  8. "Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement."Mol. Cell 35:841-855(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]