T-Cell Lymphoma Invasion And Metastasis Inducing Protein 2 (TIAM2)

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STEF; SIF and TIAM1-like exchange factor

T-Cell Lymphoma Invasion And Metastasis Inducing Protein 2 (TIAM2)
TIAM2 encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described.The cDNA for the larger message encodes a deduced 1,077-amino acid protein, whereas that for the smaller message encodes a deduced 626-amino acid protein. Both contain homology to the Dbl-homologous region (70%) and pleckstrin-homologous regions (54%) of TIAM1. Purified TIAM2 protein showed GDP-GTP exchange activity.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant T-Cell Lymphoma Invasion And Metastasis Inducing Protein 2 (TIAM2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to T-Cell Lymphoma Invasion And Metastasis Inducing Protein 2 (TIAM2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to T-Cell Lymphoma Invasion And Metastasis Inducing Protein 2 (TIAM2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for T-Cell Lymphoma Invasion And Metastasis Inducing Protein 2 (TIAM2) CLIA Kit Customized Service Offer
n/a ELISA Kit for T-Cell Lymphoma Invasion And Metastasis Inducing Protein 2 (TIAM2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant T-Cell Lymphoma Invasion And Metastasis Inducing Protein 2 (TIAM2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to T-Cell Lymphoma Invasion And Metastasis Inducing Protein 2 (TIAM2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to T-Cell Lymphoma Invasion And Metastasis Inducing Protein 2 (TIAM2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for T-Cell Lymphoma Invasion And Metastasis Inducing Protein 2 (TIAM2) CLIA Kit Customized Service Offer
n/a ELISA Kit for T-Cell Lymphoma Invasion And Metastasis Inducing Protein 2 (TIAM2) ELISA Kit Customized Service Offer
  1. "Cloning and characterization of T-cell lymphoma invasion and metastasis 2 (TIAM2), a novel guanine nucleotide exchange factor related to TIAM1."Genomics 61:66-73(1999) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]