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Phosphatidylinositol Transfer Protein Alpha (PITPNa)

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PITPN; VIB1A; PtdIns transfer protein alpha; Phosphotidylinositol Transfer Protein

Phosphatidylinositol Transfer Protein Alpha (PITPNa)
CCC F745
HGNC 9001
MGI 99887
PubMed 23633038
RGD 61885
UniProt Q00169
Wiki PITPNA
PITPNa encodes a member of a family of lipid-binding proteins that transfer molecules of phosphatidylinositol or phosphatidylcholine between membrane surfaces. The protein is implicated in phospholipase C signaling and in the production of phosphatidylinositol 3,4,5-trisphosphate (PIP3) by phosphoinositide-3-kinase.
PITPN is identical to priming-specific factor-3, one of the 3 priming factors involved in the ATP-dependent priming of Ca(2+)-activated secretion. Rat PITPN shares 40% amino acid homology over its entire length with the Drosophila retinal degeneration B (rdgB) protein. Flies carrying the rdgB mutation undergo light-enhanced retinal degeneration.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphatidylinositol Transfer Protein Alpha (PITPNa) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphatidylinositol Transfer Protein Alpha (PITPNa) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphatidylinositol Transfer Protein Alpha (PITPNa) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphatidylinositol Transfer Protein Alpha (PITPNa) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphatidylinositol Transfer Protein Alpha (PITPNa) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphatidylinositol Transfer Protein Alpha (PITPNa) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphatidylinositol Transfer Protein Alpha (PITPNa) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphatidylinositol Transfer Protein Alpha (PITPNa) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphatidylinositol Transfer Protein Alpha (PITPNa) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphatidylinositol Transfer Protein Alpha (PITPNa) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphatidylinositol Transfer Protein Alpha (PITPNa) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphatidylinositol Transfer Protein Alpha (PITPNa) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphatidylinositol Transfer Protein Alpha (PITPNa) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphatidylinositol Transfer Protein Alpha (PITPNa) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphatidylinositol Transfer Protein Alpha (PITPNa) ELISA Kit Customized Service Offer
  1. "Sequence of a human cDNA encoding phosphatidylinositol transfer protein and occurrence of a related sequence in widely divergent eukaryotes."Gene 142:301-305(1994) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. , Submitted (MAR-2007) to UniProtKB
  4. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  6. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  7. "Structure-function analysis of human phosphatidylinositol transfer protein alpha bound to phosphatidylinositol."Structure 12:317-326(2004) [PubMed] [Europe PMC] [Abstract]