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Oxysterol Binding Protein Like Protein 3 (OSBPL3)

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ORP3; OSBP3; Oxysterol-Binding Protein-Related Protein 3

Oxysterol Binding Protein Like Protein 3 (OSBPL3)
CCC F699
HGNC 16370
MGI 1918970
PubMed 24326072
RGD 1564287
UniProt Q9H4L5
Wiki OSBPL3
OSBPL3 encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Several transcript variants encoding different isoforms have been identified.
Sequence analysis predicted that the 887-amino acid protein contains a C-terminal sterol-binding (SB) domain of approximately 400 amino acids that includes the OSBP motif (EQVSHHPP). It has a pleckstrin homology (PH) domain in its N terminus. ORP3 is 73% and 62% identical to OSBPL6 and OSBPL7, respectively, in the PH domain. The 3 proteins are approximately 76% identical in the SB domain.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Oxysterol Binding Protein Like Protein 3 (OSBPL3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Oxysterol Binding Protein Like Protein 3 (OSBPL3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Oxysterol Binding Protein Like Protein 3 (OSBPL3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Oxysterol Binding Protein Like Protein 3 (OSBPL3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Oxysterol Binding Protein Like Protein 3 (OSBPL3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Oxysterol Binding Protein Like Protein 3 (OSBPL3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Oxysterol Binding Protein Like Protein 3 (OSBPL3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Oxysterol Binding Protein Like Protein 3 (OSBPL3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Oxysterol Binding Protein Like Protein 3 (OSBPL3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Oxysterol Binding Protein Like Protein 3 (OSBPL3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Oxysterol Binding Protein Like Protein 3 (OSBPL3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Oxysterol Binding Protein Like Protein 3 (OSBPL3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Oxysterol Binding Protein Like Protein 3 (OSBPL3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Oxysterol Binding Protein Like Protein 3 (OSBPL3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Oxysterol Binding Protein Like Protein 3 (OSBPL3) ELISA Kit Customized Service Offer
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  2. "A family of 12 human genes containing oxysterol-binding domains."Genomics 78:185-196(2001) [PubMed] [Europe PMC] [Abstract]
  3. "ORP3 splice variants and their expression in human tissues and hematopoietic cells."DNA Cell Biol. 22:1-9(2003) [PubMed] [Europe PMC] [Abstract]
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  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "The OSBP-related protein family in humans."J. Lipid Res. 42:1203-1213(2001) [PubMed] [Europe PMC] [Abstract]
  9. "Phosphoproteome of resting human platelets."J. Proteome Res. 7:526-534(2008) [PubMed] [Europe PMC] [Abstract]
  10. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  11. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  12. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  13. "Large-scale proteomics analysis of the human kinome."Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
  14. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  15. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  16. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  17. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]