![2',5'-Oligoadenylate Synthetase 2 (OAS2)](/upload/item/img/2-5-Oligoadenylate-Synthetase-2-(OAS2)-95689.jpg)
OAS2 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.The predicted OAS2 proteins have a common 683-amino acid sequence and different 3-prime termini. By SDS-PAGE of in vitro transcription/translation products, the authors showed that 2 isoforms have molecular masses of 69 and 71 kD.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPF689Hu01 | Recombinant 2',5'-Oligoadenylate Synthetase 2 (OAS2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAF689Hu01 | Polyclonal Antibody to 2',5'-Oligoadenylate Synthetase 2 (OAS2) | WB,IHC |
MAF689Hu21 | Monoclonal Antibody to 2',5'-Oligoadenylate Synthetase 2 (OAS2) | WB | |
MAF689Hu22 | Monoclonal Antibody to 2',5'-Oligoadenylate Synthetase 2 (OAS2) | WB; IHC; ICC; IP. | |
MAF689Hu23 | Monoclonal Antibody to 2',5'-Oligoadenylate Synthetase 2 (OAS2) | WB; IHC; ICC; IP. | |
Assay Kits | SEF689Hu | ELISA Kit for 2',5'-Oligoadenylate Synthetase 2 (OAS2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant 2',5'-Oligoadenylate Synthetase 2 (OAS2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to 2',5'-Oligoadenylate Synthetase 2 (OAS2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to 2',5'-Oligoadenylate Synthetase 2 (OAS2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for 2',5'-Oligoadenylate Synthetase 2 (OAS2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for 2',5'-Oligoadenylate Synthetase 2 (OAS2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant 2',5'-Oligoadenylate Synthetase 2 (OAS2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to 2',5'-Oligoadenylate Synthetase 2 (OAS2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to 2',5'-Oligoadenylate Synthetase 2 (OAS2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for 2',5'-Oligoadenylate Synthetase 2 (OAS2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for 2',5'-Oligoadenylate Synthetase 2 (OAS2) | ELISA Kit Customized Service Offer |
Organism species: Sus scrofa; Porcine (Pig)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPF689Po01 | Recombinant 2',5'-Oligoadenylate Synthetase 2 (OAS2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | n/a | Monoclonal Antibody to 2',5'-Oligoadenylate Synthetase 2 (OAS2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to 2',5'-Oligoadenylate Synthetase 2 (OAS2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for 2',5'-Oligoadenylate Synthetase 2 (OAS2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for 2',5'-Oligoadenylate Synthetase 2 (OAS2) | ELISA Kit Customized Service Offer |
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