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Nucleolar Protein 7 (NOL7)

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RARG-1; C6orf90; NOP27; PQBP3; Nucleolar protein of 27 kDa

Nucleolar Protein 7 (NOL7)
CCC F677
HGNC 21040
MGI 1917328
PubMed 15635413
RGD 1565934
UniProt Q9UMY1
Wiki NOL7
NOL7 gene plays a role in antiangiogenic activity.Immunofluorescence and immunocytochemical studies localized NOL7 to the nucleolus in COS-7 cells. Immunofluorescence and immunocytochemical studies localized NOL7 to the nucleolus in COS-7 cells.NOL7 expression in 3 (38%) of 8 human cervical cancer cell lines. In situ hybridization using a genomic probe confirmed abnormal NOL7 expression with loss of heterozygosity in 62 to 79% of interphase nuclei in cervical cancer samples from 3 patients.
NOL7-transfected cells had decreased angiogenesis, as detected by endothelial cell marker CD31 (PECAM1), decreased ability to stimulate endothelial cell migration, decreased VEGF expression, and increased TSP1 (THBS1) expression.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nucleolar Protein 7 (NOL7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nucleolar Protein 7 (NOL7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nucleolar Protein 7 (NOL7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nucleolar Protein 7 (NOL7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nucleolar Protein 7 (NOL7) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nucleolar Protein 7 (NOL7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nucleolar Protein 7 (NOL7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nucleolar Protein 7 (NOL7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nucleolar Protein 7 (NOL7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nucleolar Protein 7 (NOL7) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nucleolar Protein 7 (NOL7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nucleolar Protein 7 (NOL7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nucleolar Protein 7 (NOL7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nucleolar Protein 7 (NOL7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nucleolar Protein 7 (NOL7) ELISA Kit Customized Service Offer
  1. "NOL7 is a nucleolar candidate tumor suppressor gene in cervical cancer that modulates the angiogenic phenotype."Oncogene 25:588-598(2006) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "Directed proteomic analysis of the human nucleolus."Curr. Biol. 12:1-11(2002) [PubMed] [Europe PMC] [Abstract]
  7. "Functional proteomic analysis of human nucleolus."Mol. Biol. Cell 13:4100-4109(2002) [PubMed] [Europe PMC] [Abstract]