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Nuclear Transcription Factor Y Gamma (NFYC)

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CBF-C; NFYg; CBFC; H1TF2A; HAP5; HSM; NF-YC; hCBF-C; CAAT box DNA-binding protein subunit C; Nuclear transcription factor Y subunit C; Transactivator HSM-1/2

Nuclear Transcription Factor Y Gamma (NFYC)
CCC F667
HGNC 7806
MGI 107901
PubMed 16287085
RGD 3173
UniProt Q13952
Wiki NFYC
Nuclear transcription factor Y subunit gamma is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes.
This gene product, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. Additional regulation, preliminarily supported by the EST database, may be represented by alternative splicing in this subunit.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF667Hu01 Recombinant Nuclear Transcription Factor Y Gamma (NFYC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF667Hu01 Polyclonal Antibody to Nuclear Transcription Factor Y Gamma (NFYC) WB; IHC; ICC; IP.
MAF667Hu21 Monoclonal Antibody to Nuclear Transcription Factor Y Gamma (NFYC) WB; IHC; ICC; IP.
Assay Kits SEF667Hu ELISA Kit for Nuclear Transcription Factor Y Gamma (NFYC) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Transcription Factor Y Gamma (NFYC) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Transcription Factor Y Gamma (NFYC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Transcription Factor Y Gamma (NFYC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Transcription Factor Y Gamma (NFYC) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Transcription Factor Y Gamma (NFYC) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Transcription Factor Y Gamma (NFYC) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Transcription Factor Y Gamma (NFYC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Transcription Factor Y Gamma (NFYC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Transcription Factor Y Gamma (NFYC) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Transcription Factor Y Gamma (NFYC) ELISA Kit Customized Service Offer
  1. "Subunit association and DNA binding activity of the heterotrimeric transcription factor NF-Y is regulated by cellular redox."J. Biol. Chem. 271:28784-28791(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning and expression of human NF-YC."Gene 193:119-125(1997) [PubMed] [Europe PMC] [Abstract]
  3. "Isolation and sequence analysis of the cDNA encoding subunit C of human CCAAT-binding transcription factor."Gene 197:161-163(1997) [PubMed] [Europe PMC] [Abstract]
  4. "Cell cycle-dependent switch of up- and down-regulation of human hsp70 gene expression by interaction between c-Myc and CBF/NF-Y."J. Biol. Chem. 274:24270-24279(1999) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "The NF-YB/NF-YC structure gives insight into DNA binding and transcription regulation by CCAAT factor NF-Y."J. Biol. Chem. 278:1336-1345(2003) [PubMed] [Europe PMC] [Abstract]
  10. "Sequence-specific transcription factor NF-Y displays histone-like DNA binding and H2B-like ubiquitination."Cell 152:132-143(2013) [PubMed] [Europe PMC] [Abstract]
  11. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]